Moderna [MRNA] vs Vertex [VRTX] Detailed Stock Comparison

TLDR: Quick Comparison Summary

Based on 19 vital metrics comparison: Moderna wins in 7 metrics, Vertex wins in 11 metrics, with 0 ties. Vertex appears stronger overall.

View Metrics Details

Vital Metrics Comparison

MetricModernaVertexBetter
P/E Ratio (TTM)24.9727.47Moderna
Price-to-Book Ratio1.055.90Moderna
Debt-to-Equity Ratio7.888.89Moderna
PEG Ratio-0.69-0.21Moderna
EV/EBITDA-1.7820.10Moderna
Profit Margin (TTM)-94.31%31.86%Vertex
Operating Margin (TTM)-638.73%38.93%Vertex
EBITDA Margin (TTM)N/A38.93%N/A
Return on Equity-27.50%22.77%Vertex
Return on Assets (TTM)-14.77%13.09%Vertex
Free Cash Flow (TTM)$-4.06B$-978.00MVertex
1-Year Return-52.87%-10.20%Vertex
Price-to-Sales Ratio (TTM)3.208.88Moderna
Enterprise Value$5.47B$96.50BVertex
EV/Revenue Ratio1.788.45Moderna
Gross Profit Margin (TTM)13.14%86.25%Vertex
Revenue per Share (TTM)$8$44Vertex
Earnings per Share (Diluted)$-7.77$14.39Vertex
Beta (Stock Volatility)1.930.44Vertex
Performance
News Sentiment
Key Stats
Valuation
Financials
Short Interest
Dividends

Moderna vs Vertex Stock Performance Analysis

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Performance Comparison

Short-term Returns

Stock1D1W1M3M6MYTD
Moderna2.79%15.28%17.28%-6.31%2.34%-32.45%
Vertex1.15%7.07%1.96%-10.54%-15.44%0.76%

Long-term Returns

Stock1Y3Y5Y10Y15Y20Y
Moderna-52.87%-76.22%-61.14%52.53%52.53%52.53%
Vertex-10.20%38.49%51.45%271.68%1,057.89%1,798.98%

News Based Sentiment: Moderna vs Vertex

Moderna

News based Sentiment: MIXED

September presented a mixed bag for Moderna, with encouraging developments in its oncology pipeline and manufacturing capacity offset by lowered financial guidance, a declining stock price, and mixed institutional investor activity. The company is actively working to diversify beyond COVID-19, but faces significant challenges in the near term.

View Moderna News Sentiment Analysis

Vertex

News based Sentiment: POSITIVE

Vertex Pharmaceuticals delivered strong financial results in Q2 2025 and raised its full-year guidance, coupled with positive developments in its pipeline and favorable analyst coverage. This combination of factors indicates a positive trajectory for the company and strengthens the investment case.

View Vertex News Sentiment Analysis

Performance & Financial Health Analysis: Moderna vs Vertex

MetricMRNAVRTX
Market Information
Market Cap i$9.86B$100.41B
Market Cap CategoryMid capLarge cap
10 Day Avg. Volume i11,903,2502,025,380
90 Day Avg. Volume i11,598,3471,632,117
Last Close$28.37$408.85
52 Week Range$23.15 - $63.69$362.50 - $519.88
% from 52W High-55.46%-21.36%
All-Time High$497.49 (Aug 09, 2021)$519.88 (Nov 04, 2024)
% from All-Time High-94.30%-21.36%
Growth Metrics
Quarterly Revenue Growth-0.41%0.12%
Quarterly Earnings Growth-0.38%0.12%
Financial Health
Profit Margin (TTM) i-0.94%0.32%
Operating Margin (TTM) i-6.39%0.39%
Return on Equity (TTM) i-0.28%0.23%
Debt to Equity (MRQ) i7.888.89
Cash & Liquidity
Book Value per Share (MRQ)$24.16$67.02
Cash per Share (MRQ)$13.19$24.90
Operating Cash Flow (TTM) i$-2,696,999,936$3.85B
Levered Free Cash Flow (TTM) i$-2,864,375,040$2.91B
Dividends
Last 12-Month Dividend Yield iN/AN/A
Last 12-Month Dividend iN/AN/A

Valuation & Enterprise Metrics Analysis: Moderna vs Vertex

MetricMRNAVRTX
Price Ratios
P/E Ratio (TTM) i24.9727.47
Forward P/E i-2.9121.06
PEG Ratio i-0.69-0.21
Price to Sales (TTM) i3.208.88
Price to Book (MRQ) i1.055.90
Market Capitalization
Market Capitalization i$9.86B$100.41B
Enterprise Value i$5.47B$96.50B
Enterprise Value Metrics
Enterprise to Revenue i1.788.45
Enterprise to EBITDA i-1.7820.10
Risk & Other Metrics
Beta i1.930.44
Book Value per Share (MRQ) i$24.16$67.02

Financial Statements Comparison: Moderna vs Vertex

Financial Metrics

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Revenue

EBITDA

Shareholders Equity

Operating Margin

Free Cash Flow

Long Term Debt

Profit Margin

Current Ratio

Operating Cash Flow

Income Statement (MRQ)

Metric (MRQ)MRNAVRTX
Revenue/Sales i$107.00M$2.96B
Cost of Goods Sold i$90.00M$407.50M
Gross Profit i$17.00M$2.56B
Research & Development i$856.00M$978.40M
Operating Income (EBIT) i$-1.05B$1.15B
EBITDA i$-917.00M$1.34B
Pre-Tax Income i$-964.00M$1.28B
Income Tax i$7.00M$250.10M
Net Income (Profit) i$-971.00M$1.03B

Balance Sheet & Liquidity Metrics (MRQ)

Metric (MRQ)MRNAVRTX
Cash & Equivalents i$1.62B$4.67B
Total Current Assets i$6.77B$10.01B
Total Current Liabilities i$1.60B$3.78B
Long-Term Debt i$702.00M$1.65B
Total Shareholders Equity i$10.07B$16.50B
Retained Earnings i$9.07B$10.25B
Property, Plant & Equipment i$1.25B$2.63B

Cash Flow Statement Comparison (MRQ)

Metric (MRQ)MRNAVRTX
Operating Cash Flow i$-691.00M$404.90M
Capital Expenditures i$-117.00M$-40.70M
Free Cash Flow i$-1.16B$778.20M
Debt Repayment iN/A$-1.30M
Common Stock Repurchase iN/A$-696.60M

Short Interest & Institutional Ownership Analysis

MetricMRNAVRTX
Shares Short i63.31M4.05M
Short Ratio i5.582.83
Short % of Float i0.23%0.02%
Average Daily Volume (10 Day) i11,903,2502,025,380
Average Daily Volume (90 Day) i11,598,3471,632,117
Shares Outstanding i386.00M256.94M
Float Shares i363.29M255.58M
% Held by Insiders i0.07%0.00%
% Held by Institutions i0.75%0.98%

Dividend Analysis & Yield Comparison: Moderna vs Vertex

MetricMRNAVRTX
Last 12-Month Dividend iN/AN/A
Last 12-Month Dividend Yield iN/AN/A
3-Year Avg Annual Dividend iN/AN/A
3-Year Avg Dividend Yield iN/AN/A
3-Year Total Dividends iN/AN/A
Ex-Dividend DateN/AN/A