Aeterna Zentaris [AEZS] vs Insmed [INSM] Detailed Stock Comparison

Aeterna Zentaris Inc.

NASDAQ
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Insmed Inc.

NASDAQ
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TLDR: Quick Comparison Summary

Based on 19 vital metrics comparison: Aeterna Zentaris Inc. wins in 10 metrics, Insmed Inc. wins in 8 metrics, with 0 ties. Aeterna Zentaris Inc. appears stronger overall.

View Metrics Details

Vital Metrics Comparison

Metric Aeterna Zentaris Inc. Insmed Inc. Better
P/E Ratio (TTM) -1.95 -22.40 Aeterna Zentaris Inc.
Price-to-Book Ratio 0.54 40.88 Aeterna Zentaris Inc.
Debt-to-Equity Ratio 1.80 101.43 Aeterna Zentaris Inc.
PEG Ratio -1.70 -1.34 Insmed Inc.
EV/EBITDA 1.10 -30.30 Aeterna Zentaris Inc.
Profit Margin (TTM) 41.07% -210.54% Aeterna Zentaris Inc.
Operating Margin (TTM) -152,750.00% -94.64% Insmed Inc.
Return on Equity -81.71% -249.28% Aeterna Zentaris Inc.
Return on Assets (TTM) -29.96% -28.99% Insmed Inc.
Free Cash Flow (TTM) $-3.47M $-967.58M Aeterna Zentaris Inc.
1-Year Return 1,281.48% -0.89% Aeterna Zentaris Inc.
Price-to-Sales Ratio (TTM) 7.38 50.18 Aeterna Zentaris Inc.
Enterprise Value $-21.86M $29.71B Insmed Inc.
EV/Revenue Ratio -9.21 48.99 Insmed Inc.
Gross Profit Margin (TTM) 35.04% 83.24% Insmed Inc.
Revenue per Share (TTM) $2 $3 Insmed Inc.
Earnings per Share (Diluted) $-2.31 $-6.35 Aeterna Zentaris Inc.
Beta (Stock Volatility) 2.26 1.10 Insmed Inc.
Short % of Float N/A 7.19% N/A

Aeterna Zentaris Inc. vs Insmed Inc. Stock Performance Analysis

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AEZS
INSM

Performance Comparison

Short-term Returns

Stock1D1W1M3M6MYTD
Aeterna Zentaris Inc.0.75%N/AN/AN/AN/AN/A
Insmed Inc.-0.40%3.49%-10.70%-32.60%-50.51%-44.98%

Long-term Returns

Stock1Y3Y5Y10Y15Y20Y
Aeterna Zentaris Inc.1,281.48%677.08%1,186.21%856.41%856.41%856.41%
Insmed Inc.-0.89%389.25%236.25%934.36%717.46%614.23%

Performance & Financial Health Analysis: Aeterna Zentaris Inc. vs Insmed Inc.

MetricAEZSINSM
Market Information
Market Cap iN/A$31.05B
Market Cap CategoryN/ALarge cap
10 Day Avg. Volume i5,7241,921,156
90 Day Avg. Volume i6,8432,308,299
Last Close$3.73$97.46
52 Week Range$0.15 - $9.32$90.39 - $212.75
% from 52W High-60.01%-54.19%
All-Time High$9.32 (May 13, 2024)$212.81 (Dec 02, 2025)
% from All-Time High-59.98%-54.20%
Growth Metrics
Quarterly Revenue Growth-1.00%1.53%
Quarterly Earnings Growth1.30%1.53%
Financial Health
Profit Margin (TTM) i0.41%-2.11%
Operating Margin (TTM) i-1,527.50%-0.95%
Return on Equity (TTM) i-0.82%-2.49%
Debt to Equity (MRQ) i1.80101.43
Cash & Liquidity
Book Value per Share (MRQ)$10.68$3.45
Cash per Share (MRQ)$24.34$6.63
Operating Cash Flow (TTM) i$-17,347,000$-935,014,016
Levered Free Cash Flow (TTM) i$-10,088,750$-534,054,880
Dividends
Last 12-Month Dividend Yield iN/AN/A
Last 12-Month Dividend iN/AN/A

Valuation & Enterprise Metrics Analysis: Aeterna Zentaris Inc. vs Insmed Inc.

MetricAEZS (Mar 31, 2025)INSM (Apr 24, 2026)
Price Ratios
P/E Ratio (TTM) i-1.95-22.40
Forward P/E i-1.70188.19
PEG Ratio i-1.70-1.34
Price to Sales (TTM) i7.3850.18
Price to Book (MRQ) i0.5440.88
Market Capitalization
Market Capitalization i$17.51M$31.05B
Enterprise Value i$-21,857,230$29.71B
Enterprise Value Metrics
Enterprise to Revenue i-9.2148.99
Enterprise to EBITDA i1.10-30.30
Risk & Other Metrics
Beta i2.261.10
Book Value per Share (MRQ) i$10.68$3.45

Financial Statements Comparison: Aeterna Zentaris Inc. vs Insmed Inc.

Financial Metrics

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Revenue

Operating Margin

Profit Margin

Long Term Debt

Income Flow Analysis

Financial Statements Comparison

Income Statement

MetricAEZS (2023)INSM (2025)
Revenue/Sales i7.26M606.42M
Cost of Goods Sold i4.28M122.94M
COGS % of Revenue i58.9%20.3%
Gross Profit i2.98M483.49M
Gross Margin i41.1%79.7%
Research & Development i2.07M771.09M
Operating Income (EBIT) i-4.72M-994.78M
Operating Margin i-64.9%-164.0%
EBITDA i-2.86M-986.38M
EBITDA Margin i-39.4%-162.7%
Pre-Tax Income i-4.45M-1.27B
Pre-Tax Income % of Revenue i-61.3%-209.7%
Income Tax i-900,6075.03M
Income Tax % of Revenue i-12.4%0.8%
Net Income (Profit) i-3.55M-1.28B
Profit Margin i-48.9%-210.5%

Balance Sheet & Liquidity Metrics

MetricAEZS (2023)INSM (2025)
Cash & Equivalents i6.67M510.45M
Total Current Assets i11.19M1.79B
Total Current Assets % of Revenue i154.1%295.9%
Total Current Liabilities i1.31M468.87M
Total Current Liabilities % of Revenue i18.0%77.3%
Long-Term Debt i1.40M573.86M
Long-Term Debt % of Revenue i19.2%94.6%
Total Shareholders Equity i21.00M738.98M
Retained Earnings i4.65M-5.64B
Retained Earnings % of Revenue i64.0%-929.5%
Property, Plant & Equipment i11.24M76.73M

Cash Flow Statement Comparison

MetricAEZS (2023)INSM (2025)
Operating Cash Flow i-2.07M-943.31M
Operating Cash Flow % of Revenue i-28.6%-155.6%
Capital Expenditures i-739,283-32.56M
Free Cash Flow i-3.47M-967.58M
FCF Margin i-47.8%-159.6%
Debt Repayment i-279,255-4.93M
Common Stock Repurchase iN/AN/A

Short Interest & Institutional Ownership Analysis

MetricAEZSINSM
Shares Short iN/A13.76M
Short Ratio iN/A5.69
Short % of Float iN/A7.19%
Shares Outstanding i1.85M214.26M
Float Shares i1.20M193.23M
% Held by Insiders i1.32%0.55%
% Held by Institutions i5.21%102.57%
% Held by Public i93.47%-3.12%

Dividend Analysis & Yield Comparison: Aeterna Zentaris Inc. vs Insmed Inc.

MetricAEZSINSM
Last 12-Month Dividend iN/AN/A
Last 12-Month Dividend Yield iN/AN/A
3-Year Avg Annual Dividend iN/AN/A
3-Year Avg Dividend Yield iN/AN/A
3-Year Total Dividends iN/AN/A
Ex-Dividend DateN/AN/A