Alkermes plc [ALKS] vs Zoetis [ZTS] Detailed Stock Comparison

Alkermes plc

NASDAQ
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Zoetis Inc.

NYSE
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TLDR: Quick Comparison Summary

Based on 21 vital metrics comparison: Alkermes plc wins in 7 metrics, Zoetis Inc. wins in 13 metrics, with 0 ties. Zoetis Inc. appears stronger overall.

View Metrics Details

Vital Metrics Comparison

Metric Alkermes plc Zoetis Inc. Better
P/E Ratio (TTM) 23.71 19.58 Zoetis Inc.
Price-to-Book Ratio 3.09 15.04 Alkermes plc
Debt-to-Equity Ratio 3.85 279.59 Alkermes plc
PEG Ratio -0.36 2.81 Zoetis Inc.
EV/EBITDA 18.26 13.96 Zoetis Inc.
Profit Margin (TTM) 16.37% 28.24% Zoetis Inc.
Operating Margin (TTM) 15.11% 34.69% Zoetis Inc.
EBITDA Margin (TTM) 15.11% 34.69% Zoetis Inc.
Return on Equity 14.72% 65.99% Zoetis Inc.
Return on Assets (TTM) 6.99% 15.26% Zoetis Inc.
Free Cash Flow (TTM) $480.33M $2.28B Zoetis Inc.
Dividend Yield N/A 1.21% N/A
1-Year Return 48.44% -51.58% Alkermes plc
Price-to-Sales Ratio (TTM) 3.83 5.26 Alkermes plc
Enterprise Value $5.13B $56.75B Zoetis Inc.
EV/Revenue Ratio 3.48 6.00 Alkermes plc
Gross Profit Margin (TTM) 87.98% 70.17% Alkermes plc
Revenue per Share (TTM) $9 $21 Zoetis Inc.
Earnings per Share (Diluted) $1.43 $6.02 Zoetis Inc.
Beta (Stock Volatility) 0.39 0.97 Alkermes plc
Short % of Float 15.90% 4.06% Zoetis Inc.

Alkermes plc vs Zoetis Inc. Stock Performance Analysis

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ALKS
ZTS

Performance Comparison

Short-term Returns

Stock1D1W1M3M6MYTD
Alkermes plc0.18%4.50%18.36%58.43%57.47%56.97%
Zoetis Inc.1.51%0.16%3.42%-31.08%-32.94%-36.81%

Long-term Returns

Stock1Y3Y5Y10Y15Y20Y
Alkermes plc48.44%37.56%81.33%7.03%166.59%137.55%
Zoetis Inc.-51.58%-53.40%-57.08%71.34%156.59%156.59%

Performance & Financial Health Analysis: Alkermes plc vs Zoetis Inc.

MetricALKSZTS
Market Information
Market Cap i$5.55B$49.75B
Market Cap CategoryMid capLarge cap
10 Day Avg. Volume i1,637,1412,727,710
90 Day Avg. Volume i2,593,0043,835,940
Last Close$44.36$167.10
52 Week Range$25.17 - $45.76$139.70 - $200.33
% from 52W High-3.06%-16.59%
All-Time High$98.50 (Feb 28, 2000)$249.27 (Dec 27, 2021)
% from All-Time High-54.96%-32.96%
Growth Metrics
Quarterly Revenue Growth-0.11%0.03%
Quarterly Earnings Growth-0.66%0.04%
Financial Health
Profit Margin (TTM) i0.16%0.28%
Operating Margin (TTM) i0.15%0.35%
Return on Equity (TTM) i0.15%0.66%
Debt to Equity (MRQ) i3.85279.59
Cash & Liquidity
Book Value per Share (MRQ)$10.99$7.84
Cash per Share (MRQ)$3.53$5.48
Operating Cash Flow (TTM) i$520.75M$2.90B
Levered Free Cash Flow (TTM) i$-363,090,624$1.79B
Dividends
Last 12-Month Dividend Yield iN/A1.21%
Last 12-Month Dividend iN/A$2.03

Valuation & Enterprise Metrics Analysis: Alkermes plc vs Zoetis Inc.

MetricALKS (Apr 26, 2026)ZTS (Apr 13, 2026)
Price Ratios
P/E Ratio (TTM) i23.7119.58
Forward P/E i48.4415.61
PEG Ratio i-0.362.81
Price to Sales (TTM) i3.835.26
Price to Book (MRQ) i3.0915.04
Market Capitalization
Market Capitalization i$5.55B$49.75B
Enterprise Value i$5.13B$56.75B
Enterprise Value Metrics
Enterprise to Revenue i3.486.00
Enterprise to EBITDA i18.2613.96
Risk & Other Metrics
Beta i0.390.97
Book Value per Share (MRQ) i$10.99$7.84

Financial Statements Comparison: Alkermes plc vs Zoetis Inc.

Financial Metrics

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Revenue

Operating Margin

Profit Margin

Long Term Debt

Income Flow Analysis

Financial Statements Comparison

Income Statement

MetricALKS (2025)ZTS (2025)
Revenue/Sales i1.48B9.47B
Cost of Goods Sold i196.46M2.67B
COGS % of Revenue i13.3%28.2%
Gross Profit i1.28B6.80B
Gross Margin i86.7%71.8%
Research & Development i323.96M698.00M
Operating Income (EBIT) i253.96M3.60B
Operating Margin i17.2%38.0%
EBITDA i330.89M4.17B
EBITDA Margin i22.4%44.1%
Pre-Tax Income i291.45M3.36B
Pre-Tax Income % of Revenue i19.7%35.5%
Income Tax i49.79M687.00M
Income Tax % of Revenue i3.4%7.3%
Net Income (Profit) i241.66M2.67B
Profit Margin i16.4%28.2%

Balance Sheet & Liquidity Metrics

MetricALKS (2025)ZTS (2025)
Cash & Equivalents i388.57M2.31B
Total Current Assets i1.93B6.77B
Total Current Assets % of Revenue i130.7%71.5%
Total Current Liabilities i543.44M2.24B
Total Current Liabilities % of Revenue i36.8%23.6%
Long-Term Debt i63.25M9.24B
Long-Term Debt % of Revenue i4.3%97.6%
Total Shareholders Equity i1.82B3.33B
Retained Earnings i-734.79M13.74B
Retained Earnings % of Revenue i-49.8%145.2%
Property, Plant & Equipment i77.21M288.00M

Cash Flow Statement Comparison

MetricALKS (2025)ZTS (2025)
Operating Cash Flow i545.23M2.78B
Operating Cash Flow % of Revenue i36.9%29.3%
Capital Expenditures i-39.33MN/A
Free Cash Flow i480.33M2.28B
FCF Margin i32.5%24.1%
Debt Repayment i0-1.35B
Common Stock Repurchase i0-3.24B

Short Interest & Institutional Ownership Analysis

MetricALKSZTS
Shares Short i19.01M15.12M
Short Ratio i7.033.60
Short % of Float i15.90%4.06%
Shares Outstanding i165.61M424.93M
Float Shares i154.04M421.29M
% Held by Insiders i1.42%0.15%
% Held by Institutions i110.87%101.50%
% Held by Public i-12.29%-1.65%

Dividend Analysis & Yield Comparison: Alkermes plc vs Zoetis Inc.

MetricALKSZTS
Last 12-Month Dividend iN/A$2.03
Last 12-Month Dividend Yield iN/A1.21%
3-Year Avg Annual Dividend iN/A$1.80
3-Year Avg Dividend Yield iN/A0.29%
3-Year Total Dividends iN/A$5.39
Ex-Dividend DateN/AJan 20, 2026