Apogee Therapeutics [APGE] vs Regeneron [REGN] Detailed Stock Comparison

Apogee Therapeutics Inc.

NASDAQ
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Regeneron Pharmaceuticals, Inc.

NASDAQ
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TLDR: Quick Comparison Summary

Based on 21 vital metrics comparison: Apogee Therapeutics Inc. wins in 2 metrics, Regeneron Pharmaceuticals, Inc. wins in 12 metrics, with 0 ties. Regeneron Pharmaceuticals, Inc. appears stronger overall.

View Metrics Details

Vital Metrics Comparison

Metric Apogee Therapeutics Inc. Regeneron Pharmaceuticals, Inc. Better
P/E Ratio (TTM) N/A 18.00 N/A
Price-to-Book Ratio 6.86 2.45 Regeneron Pharmaceuticals, Inc.
Debt-to-Equity Ratio 0.98 9.51 Apogee Therapeutics Inc.
PEG Ratio -16.61 -4.80 Regeneron Pharmaceuticals, Inc.
EV/EBITDA -19.43 16.72 Regeneron Pharmaceuticals, Inc.
Profit Margin (TTM) 0.00% 31.41% Regeneron Pharmaceuticals, Inc.
Operating Margin (TTM) 0.00% 23.13% Regeneron Pharmaceuticals, Inc.
EBITDA Margin (TTM) N/A 23.13% N/A
Return on Equity -31.57% 14.86% Regeneron Pharmaceuticals, Inc.
Return on Assets (TTM) -21.11% 5.91% Regeneron Pharmaceuticals, Inc.
Free Cash Flow (TTM) $-232.60M $3.77B Regeneron Pharmaceuticals, Inc.
Dividend Yield N/A 0.59% N/A
1-Year Return 124.18% 25.39% Apogee Therapeutics Inc.
Price-to-Sales Ratio (TTM) N/A 5.50 N/A
Enterprise Value $5.52B $70.98B Regeneron Pharmaceuticals, Inc.
EV/Revenue Ratio N/A 4.95 N/A
Gross Profit Margin (TTM) N/A 84.95% N/A
Revenue per Share (TTM) N/A $137 N/A
Earnings per Share (Diluted) $-4.22 $41.48 Regeneron Pharmaceuticals, Inc.
Beta (Stock Volatility) 1.03 0.40 Regeneron Pharmaceuticals, Inc.
Short % of Float 22.28% 2.55% Regeneron Pharmaceuticals, Inc.

Apogee Therapeutics Inc. vs Regeneron Pharmaceuticals, Inc. Stock Performance Analysis

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APGE
REGN

Performance Comparison

Short-term Returns

Stock1D1W1M3M6MYTD
Apogee Therapeutics Inc.6.96%8.28%0.77%22.91%12.93%11.10%
Regeneron Pharmaceuticals, Inc.2.66%-1.40%-12.73%-19.27%-14.47%-20.27%

Long-term Returns

Stock1Y3Y5Y10Y15Y20Y
Apogee Therapeutics Inc.124.18%286.91%286.91%286.91%286.91%286.91%
Regeneron Pharmaceuticals, Inc.25.39%-16.92%20.10%53.41%959.24%4,557.42%

Performance & Financial Health Analysis: Apogee Therapeutics Inc. vs Regeneron Pharmaceuticals, Inc.

MetricAPGEREGN
Market Information
Market Cap i$6.59B$80.98B
Market Cap CategoryMid capLarge cap
10 Day Avg. Volume i626,497642,495
90 Day Avg. Volume i1,054,386617,765
Last Close$84.19$618.95
52 Week Range$34.34 - $95.32$476.49 - $821.11
% from 52W High-11.67%-24.62%
All-Time High$95.32 (Apr 17, 2026)$1,211.20 (Aug 26, 2024)
% from All-Time High-11.68%-48.90%
Growth Metrics
Quarterly Revenue GrowthN/A0.03%
Quarterly Earnings GrowthN/A-0.08%
Financial Health
Profit Margin (TTM) i0.00%0.31%
Operating Margin (TTM) i0.00%0.23%
Return on Equity (TTM) i-0.32%0.15%
Debt to Equity (MRQ) i0.989.51
Cash & Liquidity
Book Value per Share (MRQ)$13.21$304.65
Cash per Share (MRQ)$10.61$83.86
Operating Cash Flow (TTM) i$-227,450,000$4.98B
Levered Free Cash Flow (TTM) i$-138,978,880$3.26B
Dividends
Last 12-Month Dividend Yield iN/A0.59%
Last 12-Month Dividend iN/A$4.46

Valuation & Enterprise Metrics Analysis: Apogee Therapeutics Inc. vs Regeneron Pharmaceuticals, Inc.

MetricAPGE (Apr 24, 2026)REGN (Apr 24, 2026)
Price Ratios
P/E Ratio (TTM) iN/A18.00
Forward P/E i-16.6114.21
PEG Ratio i-16.61-4.80
Price to Sales (TTM) iN/A5.50
Price to Book (MRQ) i6.862.45
Market Capitalization
Market Capitalization i$6.59B$80.98B
Enterprise Value i$5.52B$70.98B
Enterprise Value Metrics
Enterprise to Revenue iN/A4.95
Enterprise to EBITDA i-19.4316.72
Risk & Other Metrics
Beta i1.030.40
Book Value per Share (MRQ) i$13.21$304.65

Financial Statements Comparison: Apogee Therapeutics Inc. vs Regeneron Pharmaceuticals, Inc.

Financial Metrics

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Revenue

Operating Margin

Profit Margin

Long Term Debt

Income Flow Analysis

Financial Statements Comparison

Income Statement

MetricAPGE (2025)REGN (2025)
Revenue/Sales i014.34B
Cost of Goods Sold iN/A2.10B
COGS % of Revenue i-14.6%
Gross Profit iN/A12.24B
Gross Margin i-85.4%
Research & Development i214.71M5.85B
Operating Income (EBIT) i-285.60M3.70B
Operating Margin i-25.8%
EBITDA i-284.18M5.00B
EBITDA Margin i-34.8%
Pre-Tax Income i-255.57M5.23B
Pre-Tax Income % of Revenue i-36.5%
Income Tax i278,000725.80M
Income Tax % of Revenue i-5.1%
Net Income (Profit) i-255.84M4.50B
Profit Margin i-31.4%

Balance Sheet & Liquidity Metrics

MetricAPGE (2025)REGN (2025)
Cash & Equivalents i131.55M3.12B
Total Current Assets i741.36M18.02B
Total Current Assets % of Revenue i-125.7%
Total Current Liabilities i27.91M4.37B
Total Current Liabilities % of Revenue i-30.5%
Long-Term Debt i5.35M2.71B
Long-Term Debt % of Revenue i-18.9%
Total Shareholders Equity i903.88M31.26B
Retained Earnings i-561.76M35.80B
Retained Earnings % of Revenue i-249.6%
Property, Plant & Equipment i10.16M1.54B

Cash Flow Statement Comparison

MetricAPGE (2025)REGN (2025)
Operating Cash Flow i-216.77M6.30B
Operating Cash Flow % of Revenue i-43.9%
Capital Expenditures i-5.15M0
Free Cash Flow i-232.60M3.77B
FCF Margin i-26.3%
Debt Repayment iN/AN/A
Common Stock Repurchase iN/A-3.97B

Short Interest & Institutional Ownership Analysis

MetricAPGEREGN
Shares Short i9.73M2.55M
Short Ratio i7.444.46
Short % of Float i22.28%2.55%
Shares Outstanding i68.40M105.72M
Float Shares i52.93M98.55M
% Held by Insiders i5.44%1.98%
% Held by Institutions i127.67%91.08%
% Held by Public i-33.11%6.94%

Dividend Analysis & Yield Comparison: Apogee Therapeutics Inc. vs Regeneron Pharmaceuticals, Inc.

MetricAPGEREGN
Last 12-Month Dividend iN/A$4.46
Last 12-Month Dividend Yield iN/A0.59%
3-Year Avg Annual Dividend iN/A$1.49
3-Year Avg Dividend Yield iN/A0.13%
3-Year Total Dividends iN/A$4.46
Ex-Dividend DateN/AFeb 20, 2026