Axogen [AXGN] vs Establishment Labs [ESTA] Detailed Stock Comparison
TLDR: Quick Comparison Summary
Based on 19 vital metrics comparison: Axogen Inc. wins in 14 metrics, Establishment Labs Holdings Inc. wins in 5 metrics, with 0 ties. Axogen Inc. appears stronger overall.
View Metrics Details
Vital Metrics Comparison
| Metric | Axogen Inc. | Establishment Labs Holdings Inc. | Better |
|---|---|---|---|
| P/E Ratio (TTM) | -110.18 | -37.89 | Establishment Labs Holdings Inc. |
| Price-to-Book Ratio | 13.15 | 79.68 | Axogen Inc. |
| Debt-to-Equity Ratio | 55.50 | 1,123.15 | Axogen Inc. |
| PEG Ratio | 0.04 | 0.41 | Axogen Inc. |
| EV/EBITDA | -2,165.44 | -70.21 | Establishment Labs Holdings Inc. |
| Profit Margin (TTM) | -6.97% | -24.19% | Axogen Inc. |
| Operating Margin (TTM) | -16.31% | -6.08% | Establishment Labs Holdings Inc. |
| Return on Equity | -13.49% | -133.25% | Axogen Inc. |
| Return on Assets (TTM) | -2.31% | -6.93% | Axogen Inc. |
| Free Cash Flow (TTM) | $-4.78M | $-57.61M | Axogen Inc. |
| 1-Year Return | 341.03% | 119.39% | Axogen Inc. |
| Price-to-Sales Ratio (TTM) | 8.27 | 8.92 | Axogen Inc. |
| Enterprise Value | $1.89B | $2.07B | Establishment Labs Holdings Inc. |
| EV/Revenue Ratio | 8.40 | 9.79 | Axogen Inc. |
| Gross Profit Margin (TTM) | 74.13% | 70.46% | Axogen Inc. |
| Revenue per Share (TTM) | $5 | $7 | Establishment Labs Holdings Inc. |
| Earnings per Share (Diluted) | $-0.34 | $-1.72 | Axogen Inc. |
| Beta (Stock Volatility) | 0.98 | 1.08 | Axogen Inc. |
| Short % of Float | 6.92% | 22.26% | Axogen Inc. |
Axogen Inc. vs Establishment Labs Holdings Inc. Stock Performance Analysis
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Performance Comparison
Short-term Returns
| Stock | 1D | 1W | 1M | 3M | 6M | YTD |
|---|---|---|---|---|---|---|
| Axogen Inc. | 1.72% | 5.50% | 6.71% | 33.19% | 46.88% | 41.10% |
| Establishment Labs Holdings Inc. | 2.52% | 12.52% | 28.06% | 32.66% | 16.91% | 22.33% |
Long-term Returns
| Stock | 1Y | 3Y | 5Y | 10Y | 15Y | 20Y |
|---|---|---|---|---|---|---|
| Axogen Inc. | 341.03% | 367.90% | 106.53% | 628.81% | 1,769.57% | 12,185.71% |
| Establishment Labs Holdings Inc. | 119.39% | 25.90% | 5.07% | 211.25% | 211.25% | 211.25% |
Performance & Financial Health Analysis: Axogen Inc. vs Establishment Labs Holdings Inc.
| Metric | AXGN | ESTA |
|---|---|---|
| Market Information | ||
| Market Cap | $1.94B | $1.91B |
| Market Cap Category | Small cap | Small cap |
| 10 Day Avg. Volume | 1,245,238 | 451,437 |
| 90 Day Avg. Volume | 1,068,353 | 478,309 |
| Last Close | $43.74 | $84.21 |
| 52 Week Range | $9.22 - $45.83 | $33.35 - $86.00 |
| % from 52W High | -4.56% | -2.08% |
| All-Time High | $56.85 (Jul 23, 2018) | $93.80 (Apr 18, 2022) |
| % from All-Time High | -23.06% | -10.22% |
| Growth Metrics | ||
| Quarterly Revenue Growth | 0.21% | 0.45% |
| Quarterly Earnings Growth | 0.21% | 0.45% |
| Financial Health | ||
| Profit Margin (TTM) | -0.07% | -0.24% |
| Operating Margin (TTM) | -0.16% | -0.06% |
| Return on Equity (TTM) | -0.13% | -1.33% |
| Debt to Equity (MRQ) | 55.50 | 1,123.15 |
| Cash & Liquidity | ||
| Book Value per Share (MRQ) | $2.73 | $0.80 |
| Cash per Share (MRQ) | $0.80 | $2.58 |
| Operating Cash Flow (TTM) | $812,000 | $-50,890,000 |
| Levered Free Cash Flow (TTM) | $3.58M | $-41,574,000 |
| Dividends | ||
| Last 12-Month Dividend Yield | N/A | N/A |
| Last 12-Month Dividend | $0.00 | N/A |
Valuation & Enterprise Metrics Analysis: Axogen Inc. vs Establishment Labs Holdings Inc.
| Metric | AXGN (Apr 24, 2026) | ESTA (Apr 24, 2026) |
|---|---|---|
| Price Ratios | ||
| P/E Ratio (TTM) | -110.18 | -37.89 |
| Forward P/E | 47.31 | 316.35 |
| PEG Ratio | 0.04 | 0.41 |
| Price to Sales (TTM) | 8.27 | 8.92 |
| Price to Book (MRQ) | 13.15 | 79.68 |
| Market Capitalization | ||
| Market Capitalization | $1.94B | $1.91B |
| Enterprise Value | $1.89B | $2.07B |
| Enterprise Value Metrics | ||
| Enterprise to Revenue | 8.40 | 9.79 |
| Enterprise to EBITDA | -2,165.44 | -70.21 |
| Risk & Other Metrics | ||
| Beta | 0.98 | 1.08 |
| Book Value per Share (MRQ) | $2.73 | $0.80 |
Financial Statements Comparison: Axogen Inc. vs Establishment Labs Holdings Inc.
Financial Metrics
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Revenue
Operating Margin
Profit Margin
Long Term Debt
Income Flow Analysis
Financial Statements Comparison
Income Statement
| Metric | AXGN (2025) | ESTA (2025) |
|---|---|---|
| Revenue/Sales | 225.21M | 211.08M |
| Cost of Goods Sold | 57.86M | 64.77M |
| COGS % of Revenue | 25.7% | 30.7% |
| Gross Profit | 167.35M | 146.31M |
| Gross Margin | 74.3% | 69.3% |
| Research & Development | 32.89M | 20.25M |
| Operating Income (EBIT) | -7.85M | -39.01M |
| Operating Margin | -3.5% | -18.5% |
| EBITDA | 826,000 | -22.29M |
| EBITDA Margin | 0.4% | -10.6% |
| Pre-Tax Income | -15.70M | -58.02M |
| Pre-Tax Income % of Revenue | -7.0% | -27.5% |
| Income Tax | N/A | -6.96M |
| Income Tax % of Revenue | 0.0% | -3.3% |
| Net Income (Profit) | -15.70M | -51.06M |
| Profit Margin | -7.0% | -24.2% |
Balance Sheet & Liquidity Metrics
| Metric | AXGN (2025) | ESTA (2025) |
|---|---|---|
| Cash & Equivalents | 35.55M | 75.57M |
| Total Current Assets | 120.42M | 249.94M |
| Total Current Assets % of Revenue | 53.5% | 118.4% |
| Total Current Liabilities | 23.56M | 82.14M |
| Total Current Liabilities % of Revenue | 10.5% | 38.9% |
| Long-Term Debt | 65.26M | 250.34M |
| Long-Term Debt % of Revenue | 29.0% | 118.6% |
| Total Shareholders Equity | 128.85M | 23.55M |
| Retained Earnings | -306.96M | -495.76M |
| Retained Earnings % of Revenue | -136.3% | -234.9% |
| Property, Plant & Equipment | 29.38M | 4.34M |
Cash Flow Statement Comparison
| Metric | AXGN (2025) | ESTA (2025) |
|---|---|---|
| Operating Cash Flow | 10.26M | -50.78M |
| Operating Cash Flow % of Revenue | 4.6% | -24.1% |
| Capital Expenditures | -3.75M | -6.05M |
| Free Cash Flow | -4.78M | -57.61M |
| FCF Margin | -2.1% | -27.3% |
| Debt Repayment | -32,000 | -1.02M |
| Common Stock Repurchase | N/A | N/A |
Short Interest & Institutional Ownership Analysis
| Metric | AXGN | ESTA |
|---|---|---|
| Shares Short | 3.50M | 5.22M |
| Short Ratio | 4.04 | 9.90 |
| Short % of Float | 6.92% | 22.26% |
| Shares Outstanding | 47.20M | 29.30M |
| Float Shares | 50.75M | 19.22M |
| % Held by Insiders | 2.12% | 10.16% |
| % Held by Institutions | 88.11% | 102.08% |
| % Held by Public | 9.77% | -12.24% |
Dividend Analysis & Yield Comparison: Axogen Inc. vs Establishment Labs Holdings Inc.
| Metric | AXGN | ESTA |
|---|---|---|
| Last 12-Month Dividend | $0.00 | N/A |
| Last 12-Month Dividend Yield | N/A | N/A |
| 3-Year Avg Annual Dividend | $0.00 | N/A |
| 3-Year Avg Dividend Yield | N/A | N/A |
| 3-Year Total Dividends | $0.00 | N/A |
| Ex-Dividend Date | N/A | N/A |