Establishment Labs [ESTA] vs Axogen [AXGN] Detailed Stock Comparison

Establishment Labs Holdings Inc.

NASDAQ
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Axogen Inc.

NASDAQ
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TLDR: Quick Comparison Summary

Based on 19 vital metrics comparison: Establishment Labs Holdings Inc. wins in 5 metrics, Axogen Inc. wins in 14 metrics, with 0 ties. Axogen Inc. appears stronger overall.

View Metrics Details

Vital Metrics Comparison

Metric Establishment Labs Holdings Inc. Axogen Inc. Better
P/E Ratio (TTM) -37.89 -110.18 Establishment Labs Holdings Inc.
Price-to-Book Ratio 79.68 13.15 Axogen Inc.
Debt-to-Equity Ratio 1,123.15 55.50 Axogen Inc.
PEG Ratio 0.41 0.04 Axogen Inc.
EV/EBITDA -70.21 -2,165.44 Establishment Labs Holdings Inc.
Profit Margin (TTM) -24.19% -6.97% Axogen Inc.
Operating Margin (TTM) -6.08% -16.31% Establishment Labs Holdings Inc.
Return on Equity -133.25% -13.49% Axogen Inc.
Return on Assets (TTM) -6.93% -2.31% Axogen Inc.
Free Cash Flow (TTM) $-57.61M $-4.78M Axogen Inc.
1-Year Return 119.39% 341.03% Axogen Inc.
Price-to-Sales Ratio (TTM) 8.92 8.27 Axogen Inc.
Enterprise Value $2.07B $1.89B Establishment Labs Holdings Inc.
EV/Revenue Ratio 9.79 8.40 Axogen Inc.
Gross Profit Margin (TTM) 70.46% 74.13% Axogen Inc.
Revenue per Share (TTM) $7 $5 Establishment Labs Holdings Inc.
Earnings per Share (Diluted) $-1.72 $-0.34 Axogen Inc.
Beta (Stock Volatility) 1.08 0.98 Axogen Inc.
Short % of Float 22.26% 6.92% Axogen Inc.

Establishment Labs Holdings Inc. vs Axogen Inc. Stock Performance Analysis

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ESTA
AXGN

Performance Comparison

Short-term Returns

Stock1D1W1M3M6MYTD
Establishment Labs Holdings Inc.2.52%12.52%28.06%32.66%16.91%22.33%
Axogen Inc.1.72%5.50%6.71%33.19%46.88%41.10%

Long-term Returns

Stock1Y3Y5Y10Y15Y20Y
Establishment Labs Holdings Inc.119.39%25.90%5.07%211.25%211.25%211.25%
Axogen Inc.341.03%367.90%106.53%628.81%1,769.57%12,185.71%

Performance & Financial Health Analysis: Establishment Labs Holdings Inc. vs Axogen Inc.

MetricESTAAXGN
Market Information
Market Cap i$1.91B$1.94B
Market Cap CategorySmall capSmall cap
10 Day Avg. Volume i451,4371,245,238
90 Day Avg. Volume i478,3091,068,353
Last Close$84.21$43.74
52 Week Range$33.35 - $86.00$9.22 - $45.83
% from 52W High-2.08%-4.56%
All-Time High$93.80 (Apr 18, 2022)$56.85 (Jul 23, 2018)
% from All-Time High-10.22%-23.06%
Growth Metrics
Quarterly Revenue Growth0.45%0.21%
Quarterly Earnings Growth0.45%0.21%
Financial Health
Profit Margin (TTM) i-0.24%-0.07%
Operating Margin (TTM) i-0.06%-0.16%
Return on Equity (TTM) i-1.33%-0.13%
Debt to Equity (MRQ) i1,123.1555.50
Cash & Liquidity
Book Value per Share (MRQ)$0.80$2.73
Cash per Share (MRQ)$2.58$0.80
Operating Cash Flow (TTM) i$-50,890,000$812,000
Levered Free Cash Flow (TTM) i$-41,574,000$3.58M
Dividends
Last 12-Month Dividend Yield iN/AN/A
Last 12-Month Dividend iN/A$0.00

Valuation & Enterprise Metrics Analysis: Establishment Labs Holdings Inc. vs Axogen Inc.

MetricESTA (Apr 24, 2026)AXGN (Apr 24, 2026)
Price Ratios
P/E Ratio (TTM) i-37.89-110.18
Forward P/E i316.3547.31
PEG Ratio i0.410.04
Price to Sales (TTM) i8.928.27
Price to Book (MRQ) i79.6813.15
Market Capitalization
Market Capitalization i$1.91B$1.94B
Enterprise Value i$2.07B$1.89B
Enterprise Value Metrics
Enterprise to Revenue i9.798.40
Enterprise to EBITDA i-70.21-2,165.44
Risk & Other Metrics
Beta i1.080.98
Book Value per Share (MRQ) i$0.80$2.73

Financial Statements Comparison: Establishment Labs Holdings Inc. vs Axogen Inc.

Financial Metrics

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Revenue

Operating Margin

Profit Margin

Long Term Debt

Income Flow Analysis

Financial Statements Comparison

Income Statement

MetricESTA (2025)AXGN (2025)
Revenue/Sales i211.08M225.21M
Cost of Goods Sold i64.77M57.86M
COGS % of Revenue i30.7%25.7%
Gross Profit i146.31M167.35M
Gross Margin i69.3%74.3%
Research & Development i20.25M32.89M
Operating Income (EBIT) i-39.01M-7.85M
Operating Margin i-18.5%-3.5%
EBITDA i-22.29M826,000
EBITDA Margin i-10.6%0.4%
Pre-Tax Income i-58.02M-15.70M
Pre-Tax Income % of Revenue i-27.5%-7.0%
Income Tax i-6.96MN/A
Income Tax % of Revenue i-3.3%0.0%
Net Income (Profit) i-51.06M-15.70M
Profit Margin i-24.2%-7.0%

Balance Sheet & Liquidity Metrics

MetricESTA (2025)AXGN (2025)
Cash & Equivalents i75.57M35.55M
Total Current Assets i249.94M120.42M
Total Current Assets % of Revenue i118.4%53.5%
Total Current Liabilities i82.14M23.56M
Total Current Liabilities % of Revenue i38.9%10.5%
Long-Term Debt i250.34M65.26M
Long-Term Debt % of Revenue i118.6%29.0%
Total Shareholders Equity i23.55M128.85M
Retained Earnings i-495.76M-306.96M
Retained Earnings % of Revenue i-234.9%-136.3%
Property, Plant & Equipment i4.34M29.38M

Cash Flow Statement Comparison

MetricESTA (2025)AXGN (2025)
Operating Cash Flow i-50.78M10.26M
Operating Cash Flow % of Revenue i-24.1%4.6%
Capital Expenditures i-6.05M-3.75M
Free Cash Flow i-57.61M-4.78M
FCF Margin i-27.3%-2.1%
Debt Repayment i-1.02M-32,000
Common Stock Repurchase iN/AN/A

Short Interest & Institutional Ownership Analysis

MetricESTAAXGN
Shares Short i5.22M3.50M
Short Ratio i9.904.04
Short % of Float i22.26%6.92%
Shares Outstanding i29.30M47.20M
Float Shares i19.22M50.75M
% Held by Insiders i10.16%2.12%
% Held by Institutions i102.08%88.11%
% Held by Public i-12.24%9.77%

Dividend Analysis & Yield Comparison: Establishment Labs Holdings Inc. vs Axogen Inc.

MetricESTAAXGN
Last 12-Month Dividend iN/A$0.00
Last 12-Month Dividend Yield iN/AN/A
3-Year Avg Annual Dividend iN/A$0.00
3-Year Avg Dividend Yield iN/AN/A
3-Year Total Dividends iN/A$0.00
Ex-Dividend DateN/AN/A