Exact Sciences [EXAS] vs Thermo Fisher [TMO] Detailed Stock Comparison

Exact Sciences Corp

NASDAQ
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Thermo Fisher Scientific Inc.

NYSE
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TLDR: Quick Comparison Summary

Based on 21 vital metrics comparison: Exact Sciences Corp wins in 1 metrics, Thermo Fisher Scientific Inc. wins in 17 metrics, with 0 ties. Thermo Fisher Scientific Inc. appears stronger overall.

View Metrics Details

Vital Metrics Comparison

Metric Exact Sciences Corp Thermo Fisher Scientific Inc. Better
P/E Ratio (TTM) -95.37 25.84 Thermo Fisher Scientific Inc.
Price-to-Book Ratio 8.34 3.31 Thermo Fisher Scientific Inc.
Debt-to-Equity Ratio 105.57 82.91 Thermo Fisher Scientific Inc.
PEG Ratio 55.22 2.29 Thermo Fisher Scientific Inc.
EV/EBITDA 302.23 19.02 Thermo Fisher Scientific Inc.
Profit Margin (TTM) -6.40% 15.15% Thermo Fisher Scientific Inc.
Operating Margin (TTM) -9.28% 17.89% Thermo Fisher Scientific Inc.
EBITDA Margin (TTM) N/A 17.89% N/A
Return on Equity -8.66% 13.52% Thermo Fisher Scientific Inc.
Return on Assets (TTM) -1.59% 5.00% Thermo Fisher Scientific Inc.
Free Cash Flow (TTM) $356.78M $6.29B Thermo Fisher Scientific Inc.
Dividend Yield N/A 0.38% N/A
1-Year Return 140.29% 16.53% Exact Sciences Corp
Price-to-Sales Ratio (TTM) 6.17 3.86 Thermo Fisher Scientific Inc.
Enterprise Value $21.60B $214.76B Thermo Fisher Scientific Inc.
EV/Revenue Ratio 6.65 4.75 Thermo Fisher Scientific Inc.
Gross Profit Margin (TTM) 70.11% N/A N/A
Revenue per Share (TTM) $17 $120 Thermo Fisher Scientific Inc.
Earnings per Share (Diluted) $-1.10 $18.18 Thermo Fisher Scientific Inc.
Beta (Stock Volatility) 1.44 0.97 Thermo Fisher Scientific Inc.
Short % of Float 3.92% 1.22% Thermo Fisher Scientific Inc.

Exact Sciences Corp vs Thermo Fisher Scientific Inc. Stock Performance Analysis

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EXAS
TMO

Performance Comparison

Short-term Returns

Stock1D1W1M3M6MYTD
Exact Sciences Corp0.00%1.02%1.47%3.27%100.17%3.12%
Thermo Fisher Scientific Inc.0.93%0.87%8.07%0.79%-17.74%-20.05%

Long-term Returns

Stock1Y3Y5Y10Y15Y20Y
Exact Sciences Corp140.29%54.71%-20.87%1,407.33%1,337.12%3,317.26%
Thermo Fisher Scientific Inc.16.53%-12.65%-2.72%220.94%654.32%1,231.84%

Performance & Financial Health Analysis: Exact Sciences Corp vs Thermo Fisher Scientific Inc.

MetricEXASTMO
Market Information
Market Cap i$20.03B$174.55B
Market Cap CategoryLarge capLarge cap
10 Day Avg. Volume i3,743,5832,356,220
90 Day Avg. Volume i2,715,0142,071,517
Last Close$104.91$473.72
52 Week Range$38.81 - $104.98$385.46 - $643.99
% from 52W High-0.07%-26.44%
All-Time High$159.54 (Jan 25, 2021)$672.34 (Dec 27, 2021)
% from All-Time High-34.24%-29.54%
Growth Metrics
Quarterly Revenue Growth0.23%0.06%
Quarterly Earnings Growth0.23%0.10%
Financial Health
Profit Margin (TTM) i-0.06%0.15%
Operating Margin (TTM) i-0.09%0.18%
Return on Equity (TTM) i-0.09%0.14%
Debt to Equity (MRQ) i105.5782.91
Cash & Liquidity
Book Value per Share (MRQ)$12.58$141.96
Cash per Share (MRQ)$5.05$8.75
Operating Cash Flow (TTM) i$491.44M$8.29B
Levered Free Cash Flow (TTM) i$281.87M$5.51B
Dividends
Last 12-Month Dividend Yield iN/A0.38%
Last 12-Month Dividend iN/A$1.76

Valuation & Enterprise Metrics Analysis: Exact Sciences Corp vs Thermo Fisher Scientific Inc.

MetricEXAS (Apr 07, 2026)TMO (Apr 26, 2026)
Price Ratios
P/E Ratio (TTM) i-95.3725.84
Forward P/E i55.2217.16
PEG Ratio i55.222.29
Price to Sales (TTM) i6.173.86
Price to Book (MRQ) i8.343.31
Market Capitalization
Market Capitalization i$20.03B$174.55B
Enterprise Value i$21.60B$214.76B
Enterprise Value Metrics
Enterprise to Revenue i6.654.75
Enterprise to EBITDA i302.2319.02
Risk & Other Metrics
Beta i1.440.97
Book Value per Share (MRQ) i$12.58$141.96

Financial Statements Comparison: Exact Sciences Corp vs Thermo Fisher Scientific Inc.

Financial Metrics

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Revenue

Operating Margin

Profit Margin

Long Term Debt

Income Flow Analysis

Financial Statements Comparison

Income Statement

MetricEXAS (2025)TMO (2025)
Revenue/Sales i3.25B44.56B
Cost of Goods Sold i984.24M26.32B
COGS % of Revenue i30.3%59.1%
Gross Profit i2.26B18.24B
Gross Margin i69.7%40.9%
Research & Development i523.00M1.40B
Operating Income (EBIT) i-199.10M8.11B
Operating Margin i-6.1%18.2%
EBITDA i17.87M11.86B
EBITDA Margin i0.6%26.6%
Pre-Tax Income i-203.89M7.31B
Pre-Tax Income % of Revenue i-6.3%16.4%
Income Tax i4.06M547.00M
Income Tax % of Revenue i0.1%1.2%
Net Income (Profit) i-207.95M6.72B
Profit Margin i-6.4%15.1%

Balance Sheet & Liquidity Metrics

MetricEXAS (2025)TMO (2025)
Cash & Equivalents i956.00M9.85B
Total Current Assets i1.56B28.71B
Total Current Assets % of Revenue i47.9%64.4%
Total Current Liabilities i641.15M15.19B
Total Current Liabilities % of Revenue i19.7%34.1%
Long-Term Debt i2.49B35.85B
Long-Term Debt % of Revenue i76.7%80.5%
Total Shareholders Equity i2.40B53.54B
Retained Earnings i-4.71B59.16B
Retained Earnings % of Revenue i-144.9%132.8%
Property, Plant & Equipment i122.33M0

Cash Flow Statement Comparison

MetricEXAS (2025)TMO (2025)
Operating Cash Flow i273.28M7.82B
Operating Cash Flow % of Revenue i8.4%17.5%
Capital Expenditures i-134.66M-1.48B
Free Cash Flow i356.78M6.29B
FCF Margin i11.0%14.1%
Debt Repayment i-249.17M-3.51B
Common Stock Repurchase iN/A-3.00B

Short Interest & Institutional Ownership Analysis

MetricEXASTMO
Shares Short i7.40M4.54M
Short Ratio i3.232.38
Short % of Float i3.92%1.22%
Shares Outstanding i190.80M371.62M
Float Shares i188.45M371.07M
% Held by Insiders i1.23%0.17%
% Held by Institutions i86.48%95.23%
% Held by Public i12.29%4.60%

Dividend Analysis & Yield Comparison: Exact Sciences Corp vs Thermo Fisher Scientific Inc.

MetricEXASTMO
Last 12-Month Dividend iN/A$1.76
Last 12-Month Dividend Yield iN/A0.38%
3-Year Avg Annual Dividend iN/A$1.60
3-Year Avg Dividend Yield iN/A0.08%
3-Year Total Dividends iN/A$4.80
Ex-Dividend DateN/AMar 13, 2026