Grail [GRAL] vs Charles River [CRL] Detailed Stock Comparison

Grail Inc.

NASDAQ
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Charles River Laboratories International, Inc.

NYSE
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TLDR: Quick Comparison Summary

Based on 20 vital metrics comparison: Grail Inc. wins in 4 metrics, Charles River Laboratories International, Inc. wins in 14 metrics, with 0 ties. Charles River Laboratories International, Inc. appears stronger overall.

View Metrics Details

Vital Metrics Comparison

Metric Grail Inc. Charles River Laboratories International, Inc. Better
P/E Ratio (TTM) -4.56 681.33 Charles River Laboratories International, Inc.
Price-to-Book Ratio 0.80 2.61 Grail Inc.
Debt-to-Equity Ratio 2.13 81.95 Grail Inc.
PEG Ratio 0.29 20.54 Grail Inc.
EV/EBITDA -3.29 12.23 Charles River Laboratories International, Inc.
Profit Margin (TTM) -277.46% -3.60% Charles River Laboratories International, Inc.
Operating Margin (TTM) -285.37% 4.51% Charles River Laboratories International, Inc.
EBITDA Margin (TTM) N/A 4.51% N/A
Return on Equity -16.07% -4.23% Charles River Laboratories International, Inc.
Return on Assets (TTM) -11.31% 4.24% Charles River Laboratories International, Inc.
Free Cash Flow (TTM) $-299.92M $518.49M Charles River Laboratories International, Inc.
1-Year Return 44.88% 25.47% Grail Inc.
Price-to-Sales Ratio (TTM) 14.23 2.06 Charles River Laboratories International, Inc.
Enterprise Value $1.24B $10.72B Charles River Laboratories International, Inc.
EV/Revenue Ratio 8.46 2.67 Charles River Laboratories International, Inc.
Gross Profit Margin (TTM) -25.54% 31.15% Charles River Laboratories International, Inc.
Revenue per Share (TTM) $4 $81 Charles River Laboratories International, Inc.
Earnings per Share (Diluted) $-11.11 $-2.90 Charles River Laboratories International, Inc.
Beta (Stock Volatility) N/A 1.62 N/A
Short % of Float 19.74% 10.71% Charles River Laboratories International, Inc.

Grail Inc. vs Charles River Laboratories International, Inc. Stock Performance Analysis

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GRAL
CRL

Performance Comparison

Short-term Returns

Stock1D1W1M3M6MYTD
Grail Inc.-0.07%-2.78%0.27%30.73%-34.30%-32.70%
Charles River Laboratories International, Inc.0.51%1.09%24.94%24.02%-4.89%-6.89%

Long-term Returns

Stock1Y3Y5Y10Y15Y20Y
Grail Inc.44.88%309.37%309.37%309.37%309.37%309.37%
Charles River Laboratories International, Inc.25.47%-10.71%-46.99%128.42%379.20%406.37%

Performance & Financial Health Analysis: Grail Inc. vs Charles River Laboratories International, Inc.

MetricGRALCRL
Market Information
Market Cap i$2.08B$8.28B
Market Cap CategoryMid capMid cap
10 Day Avg. Volume i823,050761,885
90 Day Avg. Volume i869,633865,618
Last Close$59.81$188.47
52 Week Range$29.95 - $118.84$143.06 - $228.88
% from 52W High-49.67%-17.66%
All-Time High$118.84 (Jan 22, 2026)$460.21 (Sep 20, 2021)
% from All-Time High-49.67%-59.05%
Growth Metrics
Quarterly Revenue Growth0.14%-0.01%
Quarterly Earnings Growth0.14%-0.01%
Financial Health
Profit Margin (TTM) i-2.77%-0.04%
Operating Margin (TTM) i-2.85%0.05%
Return on Equity (TTM) i-0.16%-0.04%
Debt to Equity (MRQ) i2.1381.95
Cash & Liquidity
Book Value per Share (MRQ)$63.92$64.30
Cash per Share (MRQ)$22.05$4.34
Operating Cash Flow (TTM) i$-299,007,008$737.65M
Levered Free Cash Flow (TTM) i$-108,893,128$572.38M
Dividends
Last 12-Month Dividend Yield iN/AN/A
Last 12-Month Dividend iN/A$0.00

Valuation & Enterprise Metrics Analysis: Grail Inc. vs Charles River Laboratories International, Inc.

MetricGRAL (Apr 24, 2026)CRL (Apr 24, 2026)
Price Ratios
P/E Ratio (TTM) i-4.56681.33
Forward P/E i-6.0613.59
PEG Ratio i0.2920.54
Price to Sales (TTM) i14.232.06
Price to Book (MRQ) i0.802.61
Market Capitalization
Market Capitalization i$2.08B$8.28B
Enterprise Value i$1.24B$10.72B
Enterprise Value Metrics
Enterprise to Revenue i8.462.67
Enterprise to EBITDA i-3.2912.23
Risk & Other Metrics
Beta iN/A1.62
Book Value per Share (MRQ) i$63.92$64.30

Financial Statements Comparison: Grail Inc. vs Charles River Laboratories International, Inc.

Financial Metrics

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Revenue

Operating Margin

Profit Margin

Long Term Debt

Income Flow Analysis

Financial Statements Comparison

Income Statement

MetricGRAL (2025)CRL (2025)
Revenue/Sales i147.17M4.02B
Cost of Goods Sold i209.75M2.69B
COGS % of Revenue i142.5%67.0%
Gross Profit i-62.57M1.32B
Gross Margin i-42.5%33.0%
Research & Development i195.79MN/A
Operating Income (EBIT) i-534.16M401.14M
Operating Margin i-363.0%10.0%
EBITDA i-349.82M786.81M
EBITDA Margin i-237.7%19.6%
Pre-Tax Income i-534.50M-99.50M
Pre-Tax Income % of Revenue i-363.2%-2.5%
Income Tax i-126.15M42.66M
Income Tax % of Revenue i-85.7%1.1%
Net Income (Profit) i-408.35M-142.16M
Profit Margin i-277.5%-3.5%

Balance Sheet & Liquidity Metrics

MetricGRAL (2025)CRL (2025)
Cash & Equivalents i249.73M213.77M
Total Current Assets i953.85M1.45B
Total Current Assets % of Revenue i648.1%36.0%
Total Current Liabilities i79.67M1.12B
Total Current Liabilities % of Revenue i54.1%27.9%
Long-Term Debt i43.15M2.57B
Long-Term Debt % of Revenue i29.3%64.0%
Total Shareholders Equity i2.58B3.21B
Retained Earnings i-10.21B1.39B
Retained Earnings % of Revenue i-6,938.6%34.6%
Property, Plant & Equipment i106.18M361.42M

Cash Flow Statement Comparison

MetricGRAL (2025)CRL (2025)
Operating Cash Flow i-315.94M194.22M
Operating Cash Flow % of Revenue i-214.7%4.8%
Capital Expenditures i-909,000N/A
Free Cash Flow i-299.92M518.49M
FCF Margin i-203.8%12.9%
Debt Repayment iN/A-1.35B
Common Stock Repurchase iN/A-360.67M

Short Interest & Institutional Ownership Analysis

MetricGRALCRL
Shares Short i7.16M4.59M
Short Ratio i7.265.18
Short % of Float i19.74%10.71%
Shares Outstanding i40.33M49.22M
Float Shares i34.63M48.66M
% Held by Insiders i4.69%0.85%
% Held by Institutions i74.52%110.31%
% Held by Public i20.79%-11.16%

Dividend Analysis & Yield Comparison: Grail Inc. vs Charles River Laboratories International, Inc.

MetricGRALCRL
Last 12-Month Dividend iN/A$0.00
Last 12-Month Dividend Yield iN/AN/A
3-Year Avg Annual Dividend iN/A$0.00
3-Year Avg Dividend Yield iN/AN/A
3-Year Total Dividends iN/A$0.00
Ex-Dividend DateN/AN/A