Illumina [ILMN] vs Danaher [DHR] Detailed Stock Comparison

TLDR: Quick Comparison Summary

Based on 21 vital metrics comparison: Illumina, Inc. wins in 10 metrics, Danaher Corporation wins in 10 metrics, with 0 ties. Both stocks appear equally matched on key metrics.

View Metrics Details

Vital Metrics Comparison

Metric Illumina, Inc. Danaher Corporation Better
P/E Ratio (TTM) 24.22 34.61 Illumina, Inc.
Price-to-Book Ratio 7.42 2.40 Danaher Corporation
Debt-to-Equity Ratio 93.76 37.17 Danaher Corporation
PEG Ratio 0.28 3.84 Illumina, Inc.
EV/EBITDA 18.53 17.69 Danaher Corporation
Profit Margin (TTM) 19.57% 14.89% Illumina, Inc.
Operating Margin (TTM) 19.67% 22.94% Danaher Corporation
EBITDA Margin (TTM) 19.67% 22.94% Danaher Corporation
Return on Equity 33.36% 7.08% Illumina, Inc.
Return on Assets (TTM) 8.39% 4.19% Illumina, Inc.
Free Cash Flow (TTM) $931.00M $5.26B Danaher Corporation
Dividend Yield N/A 0.56% N/A
1-Year Return 85.17% -10.25% Illumina, Inc.
Price-to-Sales Ratio (TTM) 4.65 5.10 Illumina, Inc.
Enterprise Value $21.10B $140.38B Danaher Corporation
EV/Revenue Ratio 4.86 5.67 Illumina, Inc.
Gross Profit Margin (TTM) 65.49% 60.34% Illumina, Inc.
Revenue per Share (TTM) $28 $35 Danaher Corporation
Earnings per Share (Diluted) $5.45 $5.16 Illumina, Inc.
Beta (Stock Volatility) 1.49 0.99 Danaher Corporation
Short % of Float 7.46% 1.10% Danaher Corporation

Illumina, Inc. vs Danaher Corporation Stock Performance Analysis

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Performance Comparison

Short-term Returns

Stock1D1W1M3M6MYTD
Illumina, Inc.3.68%5.60%17.08%39.91%23.70%24.22%
Danaher Corporation0.56%-1.32%11.85%-5.38%-20.75%-21.40%

Long-term Returns

Stock1Y3Y5Y10Y15Y20Y
Illumina, Inc.85.17%-19.62%-63.72%20.74%125.39%1,163.50%
Danaher Corporation-10.25%-15.98%-20.94%174.08%416.93%738.84%

Performance & Financial Health Analysis: Illumina, Inc. vs Danaher Corporation

MetricILMNDHR
Market Information
Market Cap i$19.18B$126.39B
Market Cap CategoryLarge capLarge cap
10 Day Avg. Volume i1,531,4655,174,666
90 Day Avg. Volume i1,454,4724,357,215
Last Close$166.89$181.10
52 Week Range$86.03 - $177.22$160.93 - $242.80
% from 52W High-5.83%-25.41%
All-Time High$540.63 (Feb 08, 2021)$296.06 (Sep 06, 2021)
% from All-Time High-69.13%-38.83%
Growth Metrics
Quarterly Revenue Growth0.05%0.04%
Quarterly Earnings Growth0.79%0.08%
Financial Health
Profit Margin (TTM) i0.20%0.15%
Operating Margin (TTM) i0.20%0.23%
Return on Equity (TTM) i0.33%0.07%
Debt to Equity (MRQ) i93.7637.17
Cash & Liquidity
Book Value per Share (MRQ)$17.80$74.32
Cash per Share (MRQ)$10.68$8.06
Operating Cash Flow (TTM) i$1.08B$6.44B
Levered Free Cash Flow (TTM) i$786.00M$4.57B
Dividends
Last 12-Month Dividend Yield iN/A0.56%
Last 12-Month Dividend iN/A$1.28

Valuation & Enterprise Metrics Analysis: Illumina, Inc. vs Danaher Corporation

MetricILMN (Apr 24, 2026)DHR (Apr 24, 2026)
Price Ratios
P/E Ratio (TTM) i24.2234.61
Forward P/E i22.6619.64
PEG Ratio i0.283.84
Price to Sales (TTM) i4.655.10
Price to Book (MRQ) i7.422.40
Market Capitalization
Market Capitalization i$19.18B$126.39B
Enterprise Value i$21.10B$140.38B
Enterprise Value Metrics
Enterprise to Revenue i4.865.67
Enterprise to EBITDA i18.5317.69
Risk & Other Metrics
Beta i1.490.99
Book Value per Share (MRQ) i$17.80$74.32

Financial Statements Comparison: Illumina, Inc. vs Danaher Corporation

Financial Metrics

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Revenue

Operating Margin

Profit Margin

Long Term Debt

Income Flow Analysis

Financial Statements Comparison

Income Statement

MetricILMN (2025)DHR (2025)
Revenue/Sales i4.34B24.57B
Cost of Goods Sold i1.47B10.05B
COGS % of Revenue i33.9%40.9%
Gross Profit i2.87B14.52B
Gross Margin i66.1%59.1%
Research & Development i967.00M1.60B
Operating Income (EBIT) i817.00M4.69B
Operating Margin i18.8%19.1%
EBITDA i1.47B7.17B
EBITDA Margin i33.8%29.2%
Pre-Tax Income i1.09B4.23B
Pre-Tax Income % of Revenue i25.0%17.2%
Income Tax i236.00M633.00M
Income Tax % of Revenue i5.4%2.6%
Net Income (Profit) i850.00M3.61B
Profit Margin i19.6%14.7%

Balance Sheet & Liquidity Metrics

MetricILMN (2025)DHR (2025)
Cash & Equivalents i1.42B4.62B
Total Current Assets i3.29B12.76B
Total Current Assets % of Revenue i75.7%51.9%
Total Current Liabilities i1.59B6.81B
Total Current Liabilities % of Revenue i36.5%27.7%
Long-Term Debt i1.98B19.50B
Long-Term Debt % of Revenue i45.5%79.4%
Total Shareholders Equity i2.72B52.54B
Retained Earnings i-392.00M46.89B
Retained Earnings % of Revenue i-9.0%190.9%
Property, Plant & Equipment i370.00M2.14B

Cash Flow Statement Comparison

MetricILMN (2025)DHR (2025)
Operating Cash Flow i1.39B5.64B
Operating Cash Flow % of Revenue i32.0%23.0%
Capital Expenditures i-148.00M-1.12B
Free Cash Flow i931.00M5.26B
FCF Margin i21.4%21.4%
Debt Repayment i-500.00M-500.00M
Common Stock Repurchase i-742.00M-3.09B

Short Interest & Institutional Ownership Analysis

MetricILMNDHR
Shares Short i6.96M6.94M
Short Ratio i4.781.68
Short % of Float i7.46%1.10%
Shares Outstanding i153.00M707.70M
Float Shares i148.62M630.65M
% Held by Insiders i0.22%10.78%
% Held by Institutions i108.01%85.08%
% Held by Public i-8.23%4.14%

Dividend Analysis & Yield Comparison: Illumina, Inc. vs Danaher Corporation

MetricILMNDHR
Last 12-Month Dividend iN/A$1.28
Last 12-Month Dividend Yield iN/A0.56%
3-Year Avg Annual Dividend iN/A$10.51
3-Year Avg Dividend Yield iN/A1.11%
3-Year Total Dividends iN/A$31.54
Ex-Dividend DateN/ADec 26, 2025