Mineralys [MLYS] vs Madrigal [MDGL] Detailed Stock Comparison

Mineralys

NASDAQ
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Madrigal

NASDAQ
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TLDR: Quick Comparison Summary

Based on 18 vital metrics comparison: Mineralys wins in 7 metrics, Madrigal wins in 8 metrics, with 0 ties. Madrigal appears stronger overall.

View Metrics Details

Vital Metrics Comparison

MetricMineralysMadrigalBetter
P/E Ratio (TTM)-10.14-19.74Madrigal
Price-to-Book Ratio7.7813.80Mineralys
Debt-to-Equity Ratio0.0017.81Mineralys
PEG Ratio0.490.27Madrigal
EV/EBITDA-10.52-29.06Madrigal
Profit Margin (TTM)0.00%-54.68%Mineralys
Operating Margin (TTM)0.00%-22.18%Mineralys
Return on Equity-63.21%-36.30%Madrigal
Return on Assets (TTM)-38.80%-18.31%Madrigal
Free Cash Flow (TTM)$-166.41M$-462.03MMineralys
1-Year Return215.48%78.75%Mineralys
Price-to-Sales Ratio (TTM)N/A18.69N/A
Enterprise Value$2.13B$8.96BMadrigal
EV/Revenue RatioN/A17.38N/A
Gross Profit Margin (TTM)N/A95.74%N/A
Revenue per Share (TTM)$0$23Madrigal
Earnings per Share (Diluted)$-3.56$-12.66Mineralys
Beta (Stock Volatility)-0.30-1.03Madrigal
Performance
News Sentiment
Key Stats
Valuation
Financials
Short Interest
Dividends

Mineralys vs Madrigal Stock Performance Analysis

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Mineralys
Madrigal
Mineralys Stock Overview | Madrigal Stock Overview

Performance Comparison

Short-term Returns

Stock1D1W1M3M6MYTD
Mineralys-0.16%6.61%174.61%148.66%182.99%202.86%
Madrigal-1.65%-0.15%20.40%45.43%32.05%37.75%

Long-term Returns

Stock1Y3Y5Y10Y15Y20Y
Mineralys215.48%101.19%101.19%101.19%101.19%101.19%
Madrigal78.75%523.60%251.74%482.51%230.19%25.37%

News Based Sentiment: Mineralys vs Madrigal

Mineralys

News based Sentiment: POSITIVE

September was a pivotal month for Mineralys Therapeutics, with positive Phase 3 trial data, a successful capital raise, and significant analyst upgrades driving substantial stock price appreciation. While dilution from the public offering and some insider selling are worth noting, the overall narrative is strongly positive, positioning the company for continued growth and potential regulatory success.

View Mineralys News Sentiment Analysis

Madrigal

News based Sentiment: POSITIVE

September was a remarkably positive month for Madrigal Pharmaceuticals, driven by a massive revenue beat, a soaring stock price, and strong analyst support. The company is actively expanding its market reach, and the overall narrative points to significant growth potential, making this a highly noteworthy month for investors.

View Madrigal News Sentiment Analysis

Performance & Financial Health Analysis: Mineralys vs Madrigal

MetricMLYSMDGL
Market Information
Market Cap i$2.88B$9.63B
Market Cap CategoryMid capMid cap
10 Day Avg. Volume i4,267,848331,490
90 Day Avg. Volume i2,045,649414,823
Last Close$37.10$432.22
52 Week Range$8.24 - $39.20$200.63 - $457.16
% from 52W High-5.36%-5.46%
All-Time High$39.20 (Sep 11, 2025)$457.16 (Sep 08, 2025)
% from All-Time High-5.36%-5.46%
Growth Metrics
Quarterly Revenue GrowthN/A13.54%
Quarterly Earnings GrowthN/A13.54%
Financial Health
Profit Margin (TTM) i0.00%-0.55%
Operating Margin (TTM) i0.00%-0.22%
Return on Equity (TTM) i-0.63%-0.36%
Debt to Equity (MRQ) i0.0017.81
Cash & Liquidity
Book Value per Share (MRQ)$4.77$31.32
Cash per Share (MRQ)$4.90$35.76
Operating Cash Flow (TTM) i$-192,684,992$-307,412,992
Levered Free Cash Flow (TTM) i$-122,116,248$-219,782,000
Dividends
Last 12-Month Dividend Yield iN/AN/A
Last 12-Month Dividend iN/AN/A

Valuation & Enterprise Metrics Analysis: Mineralys vs Madrigal

MetricMLYSMDGL
Price Ratios
P/E Ratio (TTM) i-10.14-19.74
Forward P/E i-10.69-30.96
PEG Ratio i0.490.27
Price to Sales (TTM) iN/A18.69
Price to Book (MRQ) i7.7813.80
Market Capitalization
Market Capitalization i$2.88B$9.63B
Enterprise Value i$2.13B$8.96B
Enterprise Value Metrics
Enterprise to Revenue iN/A17.38
Enterprise to EBITDA i-10.52-29.06
Risk & Other Metrics
Beta i-0.30-1.03
Book Value per Share (MRQ) i$4.77$31.32

Financial Statements Comparison: Mineralys vs Madrigal

Financial Metrics

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Revenue

EBITDA

Shareholders Equity

Operating Margin

Free Cash Flow

Long Term Debt

Profit Margin

Current Ratio

Operating Cash Flow

Income Statement (MRQ)

Metric (MRQ)MLYSMDGL
Revenue/Sales i$0$137.25M
Cost of Goods Sold iN/A$4.51M
Gross Profit iN/A$132.74M
Research & Development i$38.28M$44.17M
Operating Income (EBIT) i$-46.75M$-79.31M
EBITDA i$-46.73M$-69.56M
Pre-Tax Income i$-43.27M$-73.24M
Income Tax iN/AN/A
Net Income (Profit) i$-43.27M$-73.24M

Balance Sheet & Liquidity Metrics (MRQ)

Metric (MRQ)MLYSMDGL
Cash & Equivalents i$165.01M$183.65M
Total Current Assets i$354.51M$987.98M
Total Current Liabilities i$13.39M$167.24M
Long-Term Debt iN/A$118.76M
Total Shareholders Equity i$341.56M$710.64M
Retained Earnings i$-344.73M$-1.88B
Property, Plant & Equipment iN/A$4.01M

Cash Flow Statement Comparison (MRQ)

Metric (MRQ)MLYSMDGL
Operating Cash Flow i$-39.55M$-81.76M
Capital Expenditures i$0$0
Free Cash Flow i$-45.49M$-88.89M
Debt Repayment iN/AN/A
Common Stock Repurchase iN/AN/A

Short Interest & Institutional Ownership Analysis

MetricMLYSMDGL
Shares Short i7.62M4.05M
Short Ratio i8.489.02
Short % of Float i0.15%0.21%
Average Daily Volume (10 Day) i4,267,848331,490
Average Daily Volume (90 Day) i2,045,649414,823
Shares Outstanding i49.82M22.00M
Float Shares i46.12M10.98M
% Held by Insiders i0.02%0.08%
% Held by Institutions i0.97%1.08%

Dividend Analysis & Yield Comparison: Mineralys vs Madrigal

MetricMLYSMDGL
Last 12-Month Dividend iN/AN/A
Last 12-Month Dividend Yield iN/AN/A
3-Year Avg Annual Dividend iN/AN/A
3-Year Avg Dividend Yield iN/AN/A
3-Year Total Dividends iN/AN/A
Ex-Dividend DateN/AN/A