52-Week High
$615.00
52-Week Low
$275.00
Market Cap
$11.9B
P/E Ratio
-40.40
Div Yield
N/A

Madrigal Performance Comparison

Loading chart data...

Stock Range

Today's Range

Low: $474.52 High: $500.71
on June 15, 2026

52 Week Range

Low: $275.00 High: $615.00
on June 18, 2025

All-Time High: $614.36 on December 24, 2025

Explore how other US stocks compare to their 52-week ranges: View US Market 52-Week Insights

Key Statistics

Market Cap i $11.9B
EPS i -12.88
P/E Ratio (TTM) i -40.40
Forward P/E i 41.25
P/B Ratio i 20.00
PEG Ratio i 7.82
Div. Yield i N/A
ROE i -42.49%
Beta i -1.008
Debt to Equity i 57.68

Join Our United States Telegram Channel

Get Instant Market Updates: 52-Week High/Low Alerts, Breakout Notifications & Expert Stock Analysis Delivered To Your Phone. Join Traders Making Informed Decisions Daily!

Financial Highlights

Quarter Income Flow i

Annual Income Flow i

Peer Performance Comparison

Company Market Cap 1W 1M 3M 6M YTD 1Y 3Y 5Y 10Y 15Y 20Y
11.90B Large-cap 6.95% -4.57% 13.37% -10.84% -15.85% 62.66% 96.96% 356.96% 3,940.08% 207.30% 39.45%
Vertex
Vertex VRTX
109.45B Large-cap 1.69% 3.09% -3.36% -1.15% -0.37% -2.31% 27.89% 136.85% 413.01% 888.51% 1,245.83%
80.98B Large-cap 0.60% -11.93% -18.75% -18.29% -20.78% 15.66% -21.83% 13.80% 72.82% 1,033.17% 4,804.97%
41.87B Large-cap -1.49% 0.29% -9.76% -26.49% -28.08% -8.16% 40.32% 59.90% 405.36% 3,032.34% 1,907.45%
Insmed
Insmed INSM
31.05B Large-cap 3.49% -10.70% -32.60% -50.51% -44.98% -0.89% 389.25% 236.25% 934.36% 717.46% 614.23%
28.61B Large-cap 7.79% 9.89% 61.68% 102.61% 102.56% 279.08% 524.98% 353.09% 443.52% 443.52% 443.52%

Ownership & Short Interest

Insider Ownership i 7.71%
Institutional Ownership i 104.78%
Shares Short i 4M
Short Ratio i 10.69
Short % of Shares Outstanding i 19.65%
Average 10-Day Volume i 284K
Average 90-Day Volume i 351K

Calculate Your Madrigal Investment Returns

$

Long-Term Investment Performance Analysis

Madrigal stock price in Jul 2016 was $11.90, A $1,000.00 lump sum investment in Madrigal made 9 years ago would be worth approximately $41,996.64 today, representing a exceptional return of 4,099.66%. This translates to an annualized return (CAGR) of 45.82%.

9 Years 10 Months Investment Scenario (Jul 2016 - Jun 2026)

Initial Investment $1,000.00
Current Value $41,996.64
Annual Return (CAGR) 45.82%
Shares Owned 84.0

Investment Breakdown

Value Comparison

Disclaimer: This calculator is for informational purposes only and does not consider taxes, fees, or other costs associated with investing. Past performance does not guarantee future results.

Frequently Asked Questions

In the last 52 weeks, Madrigal reached a high of $615.00 (on N/A) and a low of $275.00 (on June 18, 2025).
Curious about Madrigal's size and valuation? Its market capitalization stands at 11.90B. When it comes to valuation, the P/E ratio (trailing twelve months) is -40.40, and the forward P/E (looking ahead) is 41.25.
As for dividends, Madrigal isn't currently offering a significant yield, or that specific data isn't available right now.

When looking at Madrigal, it can be helpful to see how it compares to other players in its field. Here are a few similar companies or key competitors:

CompanyMkt CapSectorIndustry1Y Return3Y Return
Vertex
VRTX
109.45BHealthcareBiotechnology-2.31%27.89%
Regeneron
REGN
80.98BHealthcareBiotechnology15.66%-21.83%
Alnylam
ALNY
41.87BHealthcareBiotechnology-8.16%40.32%
Insmed
INSM
31.05BHealthcareBiotechnology-0.89%389.25%
Revolution Medicines
RVMD
28.61BHealthcareBiotechnology279.08%524.98%

For a more comprehensive list, please see the Peer Performance Comparison table on this page.

To get a sense of Madrigal's financial health, here are a few key indicators: its Return on Equity (ROE) over the last twelve months is -42.49%, the Debt to Equity ratio from the most recent quarter is 57.68, and its Gross Profit Margin stands at 92.39%.
Looking at Madrigal's growth, its revenue over the trailing twelve months (TTM) was $958M. Compared to the same quarter last year (YoY), quarterly revenue grew by 210.80%, and quarterly earnings saw a YoY growth of 210.77%.
Wondering who owns Madrigal stock? Company insiders (like executives and directors) hold about 7.71% of the shares, while institutional investors (such as mutual funds and pension funds) own approximately 104.78%.

For more common questions about our data, please visit our About Data page.

Nippun Rana

Nippun Rana

Chasing the market trend!

Hi, I’m Nippun, a tech enthusiast from Haryana, India. I have been coding since 2010 and using my coding skills in the share market since 2020. I have been coding scripts in Pinescript that work on Tradingview app/web. I love learning about new technology and applying it to solve real-world problems. Coding and share-market are my passions, and I enjoy finding and fixing bugs in code. I aim to share my skill set and experience that can positively impact society. Feel free to connect with me, an...

Data is provided for informational purposes only. Devyara does not guarantee the accuracy of the data displayed.