Opko Health [OPK] vs Thermo Fisher [TMO] Detailed Stock Comparison

Opko Health Inc.

NASDAQ
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Thermo Fisher Scientific Inc.

NYSE
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TLDR: Quick Comparison Summary

Based on 21 vital metrics comparison: Opko Health Inc. wins in 5 metrics, Thermo Fisher Scientific Inc. wins in 13 metrics, with 0 ties. Thermo Fisher Scientific Inc. appears stronger overall.

View Metrics Details

Vital Metrics Comparison

Metric Opko Health Inc. Thermo Fisher Scientific Inc. Better
P/E Ratio (TTM) -4.08 25.84 Thermo Fisher Scientific Inc.
Price-to-Book Ratio 0.73 3.31 Opko Health Inc.
Debt-to-Equity Ratio 31.29 82.91 Opko Health Inc.
PEG Ratio 0.01 2.29 Opko Health Inc.
EV/EBITDA -7.53 19.02 Thermo Fisher Scientific Inc.
Profit Margin (TTM) -37.19% 15.15% Thermo Fisher Scientific Inc.
Operating Margin (TTM) -28.98% 17.89% Thermo Fisher Scientific Inc.
EBITDA Margin (TTM) N/A 17.89% N/A
Return on Equity -17.14% 13.52% Thermo Fisher Scientific Inc.
Return on Assets (TTM) -6.62% 5.00% Thermo Fisher Scientific Inc.
Free Cash Flow (TTM) $-190.82M $6.29B Thermo Fisher Scientific Inc.
Dividend Yield N/A 0.38% N/A
1-Year Return 6.77% 16.53% Thermo Fisher Scientific Inc.
Price-to-Sales Ratio (TTM) 1.54 3.86 Opko Health Inc.
Enterprise Value $958.44M $214.76B Thermo Fisher Scientific Inc.
EV/Revenue Ratio 1.58 4.75 Opko Health Inc.
Gross Profit Margin (TTM) 43.13% N/A N/A
Revenue per Share (TTM) $1 $120 Thermo Fisher Scientific Inc.
Earnings per Share (Diluted) $-0.30 $18.18 Thermo Fisher Scientific Inc.
Beta (Stock Volatility) 1.49 0.97 Thermo Fisher Scientific Inc.
Short % of Float 7.79% 1.22% Thermo Fisher Scientific Inc.

Opko Health Inc. vs Thermo Fisher Scientific Inc. Stock Performance Analysis

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OPK
TMO

Performance Comparison

Short-term Returns

Stock1D1W1M3M6MYTD
Opko Health Inc.-1.41%-2.10%27.27%17.65%3.70%10.24%
Thermo Fisher Scientific Inc.0.93%0.87%8.07%0.79%-17.74%-20.05%

Long-term Returns

Stock1Y3Y5Y10Y15Y20Y
Opko Health Inc.6.77%-8.39%-61.62%-84.31%-56.84%246.34%
Thermo Fisher Scientific Inc.16.53%-12.65%-2.72%220.94%654.32%1,231.84%

Performance & Financial Health Analysis: Opko Health Inc. vs Thermo Fisher Scientific Inc.

MetricOPKTMO
Market Information
Market Cap i$936.60M$174.55B
Market Cap CategorySmall capLarge cap
10 Day Avg. Volume i2,018,1602,356,220
90 Day Avg. Volume i2,439,2572,071,517
Last Close$1.40$473.72
52 Week Range$0.98 - $1.60$385.46 - $643.99
% from 52W High-12.50%-26.44%
All-Time High$19.20 (Jun 01, 2015)$672.34 (Dec 27, 2021)
% from All-Time High-92.71%-29.54%
Growth Metrics
Quarterly Revenue Growth-0.19%0.06%
Quarterly Earnings Growth-0.19%0.10%
Financial Health
Profit Margin (TTM) i-0.37%0.15%
Operating Margin (TTM) i-0.29%0.18%
Return on Equity (TTM) i-0.17%0.14%
Debt to Equity (MRQ) i31.2982.91
Cash & Liquidity
Book Value per Share (MRQ)$1.67$141.96
Cash per Share (MRQ)$0.48$8.75
Operating Cash Flow (TTM) i$-178,542,000$8.29B
Levered Free Cash Flow (TTM) i$-131,252,376$5.51B
Dividends
Last 12-Month Dividend Yield iN/A0.38%
Last 12-Month Dividend iN/A$1.76

Valuation & Enterprise Metrics Analysis: Opko Health Inc. vs Thermo Fisher Scientific Inc.

MetricOPK (Apr 24, 2026)TMO (Apr 26, 2026)
Price Ratios
P/E Ratio (TTM) i-4.0825.84
Forward P/E i-3.7017.16
PEG Ratio i0.012.29
Price to Sales (TTM) i1.543.86
Price to Book (MRQ) i0.733.31
Market Capitalization
Market Capitalization i$936.60M$174.55B
Enterprise Value i$958.44M$214.76B
Enterprise Value Metrics
Enterprise to Revenue i1.584.75
Enterprise to EBITDA i-7.5319.02
Risk & Other Metrics
Beta i1.490.97
Book Value per Share (MRQ) i$1.67$141.96

Financial Statements Comparison: Opko Health Inc. vs Thermo Fisher Scientific Inc.

Financial Metrics

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Revenue

Operating Margin

Profit Margin

Long Term Debt

Income Flow Analysis

Financial Statements Comparison

Income Statement

MetricOPK (2025)TMO (2025)
Revenue/Sales i606.88M44.56B
Cost of Goods Sold i400.94M26.32B
COGS % of Revenue i66.1%59.1%
Gross Profit i205.94M18.24B
Gross Margin i33.9%40.9%
Research & Development i124.03M1.40B
Operating Income (EBIT) i-218.99M8.11B
Operating Margin i-36.1%18.2%
EBITDA i-142.42M11.86B
EBITDA Margin i-23.5%26.6%
Pre-Tax Income i-241.36M7.31B
Pre-Tax Income % of Revenue i-39.8%16.4%
Income Tax i-15.71M547.00M
Income Tax % of Revenue i-2.6%1.2%
Net Income (Profit) i-225.68M6.72B
Profit Margin i-37.2%15.1%

Balance Sheet & Liquidity Metrics

MetricOPK (2025)TMO (2025)
Cash & Equivalents i369.07M9.85B
Total Current Assets i581.88M28.71B
Total Current Assets % of Revenue i95.9%64.4%
Total Current Liabilities i146.68M15.19B
Total Current Liabilities % of Revenue i24.2%34.1%
Long-Term Debt i373.92M35.85B
Long-Term Debt % of Revenue i61.6%80.5%
Total Shareholders Equity i1.27B53.54B
Retained Earnings i-2.29B59.16B
Retained Earnings % of Revenue i-377.5%132.8%
Property, Plant & Equipment i46.93M0

Cash Flow Statement Comparison

MetricOPK (2025)TMO (2025)
Operating Cash Flow i-60.19M7.82B
Operating Cash Flow % of Revenue i-9.9%17.5%
Capital Expenditures i287,000-1.48B
Free Cash Flow i-190.82M6.29B
FCF Margin i-31.4%14.1%
Debt Repayment i-103.79M-3.51B
Common Stock Repurchase i-47.04M-3.00B

Short Interest & Institutional Ownership Analysis

MetricOPKTMO
Shares Short i33.62M4.54M
Short Ratio i12.742.38
Short % of Float i7.79%1.22%
Shares Outstanding i759.07M371.62M
Float Shares i336.30M371.07M
% Held by Insiders i49.35%0.17%
% Held by Institutions i27.03%95.23%
% Held by Public i23.62%4.60%

Dividend Analysis & Yield Comparison: Opko Health Inc. vs Thermo Fisher Scientific Inc.

MetricOPKTMO
Last 12-Month Dividend iN/A$1.76
Last 12-Month Dividend Yield iN/A0.38%
3-Year Avg Annual Dividend iN/A$1.60
3-Year Avg Dividend Yield iN/A0.08%
3-Year Total Dividends iN/A$4.80
Ex-Dividend DateN/AMar 13, 2026