Praxis Precision [PRAX] vs Bio-Techne [TECH] Detailed Stock Comparison

Praxis Precision Medicines Inc.

NASDAQ
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Bio-Techne Corporation

NASDAQ
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TLDR: Quick Comparison Summary

Based on 21 vital metrics comparison: Praxis Precision Medicines Inc. wins in 2 metrics, Bio-Techne Corporation wins in 12 metrics, with 0 ties. Bio-Techne Corporation appears stronger overall.

View Metrics Details

Vital Metrics Comparison

Metric Praxis Precision Medicines Inc. Bio-Techne Corporation Better
P/E Ratio (TTM) N/A 117.16 N/A
Price-to-Book Ratio 9.46 4.55 Bio-Techne Corporation
Debt-to-Equity Ratio 0.01 20.07 Praxis Precision Medicines Inc.
PEG Ratio -38.31 -0.82 Bio-Techne Corporation
EV/EBITDA -26.32 28.87 Bio-Techne Corporation
Profit Margin (TTM) 0.00% 6.41% Bio-Techne Corporation
Operating Margin (TTM) 0.00% 14.51% Bio-Techne Corporation
EBITDA Margin (TTM) N/A 14.51% N/A
Return on Equity -45.83% 3.80% Bio-Techne Corporation
Return on Assets (TTM) -28.69% 6.09% Bio-Techne Corporation
Free Cash Flow (TTM) $-249.12M $256.55M Bio-Techne Corporation
Dividend Yield N/A 0.62% N/A
1-Year Return 501.76% 6.89% Praxis Precision Medicines Inc.
Price-to-Sales Ratio (TTM) N/A 7.35 N/A
Enterprise Value $8.58B $9.19B Bio-Techne Corporation
EV/Revenue Ratio N/A 7.56 N/A
Gross Profit Margin (TTM) N/A 62.72% N/A
Revenue per Share (TTM) N/A $8 N/A
Earnings per Share (Diluted) $-13.48 $0.49 Bio-Techne Corporation
Beta (Stock Volatility) 2.97 1.47 Bio-Techne Corporation
Short % of Float 14.21% 5.09% Bio-Techne Corporation

Praxis Precision Medicines Inc. vs Bio-Techne Corporation Stock Performance Analysis

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PRAX
TECH

Performance Comparison

Short-term Returns

Stock1D1W1M3M6MYTD
Praxis Precision Medicines Inc.-0.77%4.46%-22.78%-13.27%-4.29%-7.63%
Bio-Techne Corporation4.02%6.69%29.72%15.08%-4.29%-5.83%

Long-term Returns

Stock1Y3Y5Y10Y15Y20Y
Praxis Precision Medicines Inc.501.76%1,560.93%-17.42%-36.07%-36.07%-36.07%
Bio-Techne Corporation6.89%-31.20%-49.99%96.15%179.21%318.28%

Performance & Financial Health Analysis: Praxis Precision Medicines Inc. vs Bio-Techne Corporation

MetricPRAXTECH
Market Information
Market Cap i$9.60B$9.07B
Market Cap CategoryMid capMid cap
10 Day Avg. Volume i391,4532,151,790
90 Day Avg. Volume i416,3212,370,067
Last Close$264.54$56.17
52 Week Range$37.19 - $366.52$43.20 - $72.16
% from 52W High-27.82%-22.16%
All-Time High$914.27 (Jan 04, 2021)$135.96 (Sep 20, 2021)
% from All-Time High-71.07%-58.69%
Growth Metrics
Quarterly Revenue GrowthN/A-0.01%
Quarterly Earnings Growth-1.00%0.14%
Financial Health
Profit Margin (TTM) i0.00%0.06%
Operating Margin (TTM) i0.00%0.15%
Return on Equity (TTM) i-0.46%0.04%
Debt to Equity (MRQ) i0.0120.07
Cash & Liquidity
Book Value per Share (MRQ)$34.85$12.62
Cash per Share (MRQ)$21.52$0.93
Operating Cash Flow (TTM) i$-249,068,000$251.25M
Levered Free Cash Flow (TTM) i$-146,253,744$274.30M
Dividends
Last 12-Month Dividend Yield iN/A0.62%
Last 12-Month Dividend iN/A$0.40

Valuation & Enterprise Metrics Analysis: Praxis Precision Medicines Inc. vs Bio-Techne Corporation

MetricPRAX (Apr 26, 2026)TECH (Nov 10, 2025)
Price Ratios
P/E Ratio (TTM) iN/A117.16
Forward P/E i-38.3126.21
PEG Ratio i-38.31-0.82
Price to Sales (TTM) iN/A7.35
Price to Book (MRQ) i9.464.55
Market Capitalization
Market Capitalization i$9.60B$9.07B
Enterprise Value i$8.58B$9.19B
Enterprise Value Metrics
Enterprise to Revenue iN/A7.56
Enterprise to EBITDA i-26.3228.87
Risk & Other Metrics
Beta i2.971.47
Book Value per Share (MRQ) i$34.85$12.62

Financial Statements Comparison: Praxis Precision Medicines Inc. vs Bio-Techne Corporation

Financial Metrics

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Revenue

Operating Margin

Profit Margin

Long Term Debt

Income Flow Analysis

Financial Statements Comparison

Income Statement

MetricPRAX (2025)TECH (2025)
Revenue/Sales i01.22B
Cost of Goods Sold iN/A429.36M
COGS % of Revenue i-35.2%
Gross Profit iN/A790.27M
Gross Margin i-64.8%
Research & Development i267.12M99.50M
Operating Income (EBIT) i-326.20M242.80M
Operating Margin i-19.9%
EBITDA i-326.06M357.57M
EBITDA Margin i-29.3%
Pre-Tax Income i-303.27M98.46M
Pre-Tax Income % of Revenue i-8.1%
Income Tax iN/A25.06M
Income Tax % of Revenue i-2.1%
Net Income (Profit) i-303.27M73.40M
Profit Margin i-6.0%

Balance Sheet & Liquidity Metrics

MetricPRAX (2025)TECH (2025)
Cash & Equivalents i357.33M162.19M
Total Current Assets i610.91M608.30M
Total Current Assets % of Revenue i-49.9%
Total Current Liabilities i59.77M175.85M
Total Current Liabilities % of Revenue i-14.4%
Long-Term Debt i0429.96M
Long-Term Debt % of Revenue i-35.3%
Total Shareholders Equity i878.14M1.92B
Retained Earnings i-1.14B1.07B
Retained Earnings % of Revenue i-87.4%
Property, Plant & Equipment i415,00073.40M

Cash Flow Statement Comparison

MetricPRAX (2025)TECH (2025)
Operating Cash Flow i-257.32M185.64M
Operating Cash Flow % of Revenue i-15.2%
Capital Expenditures i-56,000-31.01M
Free Cash Flow i-249.12M256.55M
FCF Margin i-21.0%
Debt Repayment iN/A-77.00M
Common Stock Repurchase iN/A-275.73M

Short Interest & Institutional Ownership Analysis

MetricPRAXTECH
Shares Short i3.95M6.94M
Short Ratio i9.072.59
Short % of Float i14.21%5.09%
Shares Outstanding i25.20M154.97M
Float Shares i25.78M153.94M
% Held by Insiders i0.40%0.28%
% Held by Institutions i106.12%102.89%
% Held by Public i-6.52%-3.17%

Dividend Analysis & Yield Comparison: Praxis Precision Medicines Inc. vs Bio-Techne Corporation

MetricPRAXTECH
Last 12-Month Dividend iN/A$0.40
Last 12-Month Dividend Yield iN/A0.62%
3-Year Avg Annual Dividend iN/A$0.32
3-Year Avg Dividend Yield iN/A0.12%
3-Year Total Dividends iN/A$0.96
Ex-Dividend DateN/AFeb 13, 2026