QuidelOrtho [QDEL] vs Stryker [SYK] Detailed Stock Comparison
TLDR: Quick Comparison Summary
Based on 21 vital metrics comparison: QuidelOrtho Corporation wins in 5 metrics, Stryker Corporation wins in 14 metrics, with 0 ties. Stryker Corporation appears stronger overall.
View Metrics Details
Vital Metrics Comparison
| Metric | QuidelOrtho Corporation | Stryker Corporation | Better |
|---|---|---|---|
| P/E Ratio (TTM) | N/A | 39.21 | N/A |
| Price-to-Book Ratio | 0.42 | 5.62 | QuidelOrtho Corporation |
| Debt-to-Equity Ratio | 148.60 | 72.97 | Stryker Corporation |
| PEG Ratio | 4.15 | 0.72 | Stryker Corporation |
| EV/EBITDA | 6.23 | 19.90 | QuidelOrtho Corporation |
| Profit Margin (TTM) | -41.46% | 12.92% | Stryker Corporation |
| Operating Margin (TTM) | 4.01% | 27.24% | Stryker Corporation |
| EBITDA Margin (TTM) | 4.01% | 27.24% | Stryker Corporation |
| Return on Equity | -46.15% | 15.08% | Stryker Corporation |
| Return on Assets (TTM) | 1.27% | 7.92% | Stryker Corporation |
| Free Cash Flow (TTM) | $-83.00M | $4.28B | Stryker Corporation |
| Dividend Yield | N/A | 0.97% | N/A |
| 1-Year Return | -57.55% | -20.27% | Stryker Corporation |
| Price-to-Sales Ratio (TTM) | 0.30 | 5.02 | QuidelOrtho Corporation |
| Enterprise Value | $3.50B | $138.30B | Stryker Corporation |
| EV/Revenue Ratio | 1.28 | 5.51 | QuidelOrtho Corporation |
| Gross Profit Margin (TTM) | 44.28% | 64.54% | Stryker Corporation |
| Revenue per Share (TTM) | $40 | $66 | Stryker Corporation |
| Earnings per Share (Diluted) | $-16.69 | $8.40 | Stryker Corporation |
| Beta (Stock Volatility) | 0.92 | 0.93 | QuidelOrtho Corporation |
| Short % of Float | 31.16% | 1.20% | Stryker Corporation |
QuidelOrtho Corporation vs Stryker Corporation Stock Performance Analysis
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Performance Comparison
Short-term Returns
| Stock | 1D | 1W | 1M | 3M | 6M | YTD |
|---|---|---|---|---|---|---|
| QuidelOrtho Corporation | 2.33% | 10.84% | 7.00% | -41.19% | -49.91% | -53.82% |
| Stryker Corporation | 0.58% | -6.29% | 0.83% | -24.22% | -20.01% | -15.76% |
Long-term Returns
| Stock | 1Y | 3Y | 5Y | 10Y | 15Y | 20Y |
|---|---|---|---|---|---|---|
| QuidelOrtho Corporation | -57.55% | -84.89% | -87.49% | -22.50% | -11.19% | 34.37% |
| Stryker Corporation | -20.27% | 9.63% | 21.15% | 168.66% | 406.79% | 583.29% |
Performance & Financial Health Analysis: QuidelOrtho Corporation vs Stryker Corporation
| Metric | QDEL | SYK |
|---|---|---|
| Market Information | ||
| Market Cap | $765.24M | $126.25B |
| Market Cap Category | Small cap | Large cap |
| 10 Day Avg. Volume | 3,727,559 | 1,881,406 |
| 90 Day Avg. Volume | 2,559,683 | 2,161,139 |
| Last Close | $13.60 | $295.00 |
| 52 Week Range | $9.92 - $35.58 | $281.00 - $404.87 |
| % from 52W High | -61.78% | -27.14% |
| All-Time High | $306.72 (Aug 03, 2020) | $406.19 (Jan 27, 2025) |
| % from All-Time High | -95.57% | -27.37% |
| Growth Metrics | ||
| Quarterly Revenue Growth | 0.02% | 0.11% |
| Quarterly Earnings Growth | 0.02% | 0.56% |
| Financial Health | ||
| Profit Margin (TTM) | -0.41% | 0.13% |
| Operating Margin (TTM) | 0.04% | 0.27% |
| Return on Equity (TTM) | -0.46% | 0.15% |
| Debt to Equity (MRQ) | 148.60 | 72.97 |
| Cash & Liquidity | ||
| Book Value per Share (MRQ) | $28.28 | $58.61 |
| Cash per Share (MRQ) | $2.50 | $10.71 |
| Operating Cash Flow (TTM) | $105.20M | $5.04B |
| Levered Free Cash Flow (TTM) | $233.88M | $4.17B |
| Dividends | ||
| Last 12-Month Dividend Yield | N/A | 0.97% |
| Last 12-Month Dividend | N/A | $3.40 |
Valuation & Enterprise Metrics Analysis: QuidelOrtho Corporation vs Stryker Corporation
| Metric | QDEL (Apr 24, 2026) | SYK (Apr 24, 2026) |
|---|---|---|
| Price Ratios | ||
| P/E Ratio (TTM) | N/A | 39.21 |
| Forward P/E | 4.15 | 19.67 |
| PEG Ratio | 4.15 | 0.72 |
| Price to Sales (TTM) | 0.30 | 5.02 |
| Price to Book (MRQ) | 0.42 | 5.62 |
| Market Capitalization | ||
| Market Capitalization | $765.24M | $126.25B |
| Enterprise Value | $3.50B | $138.30B |
| Enterprise Value Metrics | ||
| Enterprise to Revenue | 1.28 | 5.51 |
| Enterprise to EBITDA | 6.23 | 19.90 |
| Risk & Other Metrics | ||
| Beta | 0.92 | 0.93 |
| Book Value per Share (MRQ) | $28.28 | $58.61 |
Financial Statements Comparison: QuidelOrtho Corporation vs Stryker Corporation
Financial Metrics
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Revenue
Operating Margin
Profit Margin
Long Term Debt
Income Flow Analysis
Financial Statements Comparison
Income Statement
| Metric | QDEL (2025) | SYK (2025) |
|---|---|---|
| Revenue/Sales | 2.73B | 25.12B |
| Cost of Goods Sold | 1.46B | 9.05B |
| COGS % of Revenue | 53.3% | 36.0% |
| Gross Profit | 1.27B | 16.07B |
| Gross Margin | 46.7% | 64.0% |
| Research & Development | 186.20M | 1.62B |
| Operating Income (EBIT) | 54.80M | 5.06B |
| Operating Margin | 2.0% | 20.1% |
| EBITDA | 488.50M | 6.48B |
| EBITDA Margin | 17.9% | 25.8% |
| Pre-Tax Income | -1.11B | 4.51B |
| Pre-Tax Income % of Revenue | -40.6% | 18.0% |
| Income Tax | 24.10M | 1.27B |
| Income Tax % of Revenue | 0.9% | 5.0% |
| Net Income (Profit) | -1.13B | 3.25B |
| Profit Margin | -41.5% | 12.9% |
Balance Sheet & Liquidity Metrics
| Metric | QDEL (2025) | SYK (2025) |
|---|---|---|
| Cash & Equivalents | 169.80M | 4.01B |
| Total Current Assets | 1.45B | 14.76B |
| Total Current Assets % of Revenue | 53.0% | 58.7% |
| Total Current Liabilities | 966.10M | 7.79B |
| Total Current Liabilities % of Revenue | 35.4% | 31.0% |
| Long-Term Debt | 2.63B | 14.86B |
| Long-Term Debt % of Revenue | 96.2% | 59.2% |
| Total Shareholders Equity | 1.92B | 22.42B |
| Retained Earnings | -996.00M | 20.47B |
| Retained Earnings % of Revenue | -36.5% | 81.5% |
| Property, Plant & Equipment | 1.06B | 1.79B |
Cash Flow Statement Comparison
| Metric | QDEL (2025) | SYK (2025) |
|---|---|---|
| Operating Cash Flow | -770.50M | 4.70B |
| Operating Cash Flow % of Revenue | -28.2% | 18.7% |
| Capital Expenditures | -188.20M | -761.00M |
| Free Cash Flow | -83.00M | 4.28B |
| FCF Margin | -3.0% | 17.1% |
| Debt Repayment | -2.41B | -1.40B |
| Common Stock Repurchase | 0 | N/A |
Short Interest & Institutional Ownership Analysis
| Metric | QDEL | SYK |
|---|---|---|
| Shares Short | 12.79M | 4.42M |
| Short Ratio | 7.64 | 1.95 |
| Short % of Float | 31.16% | 1.20% |
| Shares Outstanding | 67.93M | 382.50M |
| Float Shares | 63.58M | 346.55M |
| % Held by Insiders | 1.01% | 5.37% |
| % Held by Institutions | 115.01% | 82.09% |
| % Held by Public | -16.02% | 12.54% |
Dividend Analysis & Yield Comparison: QuidelOrtho Corporation vs Stryker Corporation
| Metric | QDEL | SYK |
|---|---|---|
| Last 12-Month Dividend | N/A | $3.40 |
| Last 12-Month Dividend Yield | N/A | 0.97% |
| 3-Year Avg Annual Dividend | N/A | $3.23 |
| 3-Year Avg Dividend Yield | N/A | 0.24% |
| 3-Year Total Dividends | N/A | $9.69 |
| Ex-Dividend Date | N/A | Dec 31, 2025 |