Scholar Rock Holding [SRRK] vs Madrigal [MDGL] Detailed Stock Comparison

Scholar Rock Holding

NASDAQ
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Madrigal

NASDAQ
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TLDR: Quick Comparison Summary

Based on 18 vital metrics comparison: Scholar Rock Holding wins in 6 metrics, Madrigal wins in 9 metrics, with 0 ties. Madrigal appears stronger overall.

View Metrics Details

Vital Metrics Comparison

MetricScholar Rock HoldingMadrigalBetter
P/E Ratio (TTM)-15.08-20.87Madrigal
Price-to-Book Ratio15.7914.15Madrigal
Debt-to-Equity Ratio26.3717.81Madrigal
PEG Ratio-0.240.28Scholar Rock Holding
EV/EBITDA-10.74-29.84Madrigal
Profit Margin (TTM)0.00%-54.68%Scholar Rock Holding
Operating Margin (TTM)0.00%-22.18%Scholar Rock Holding
Return on Equity-172.08%-36.30%Madrigal
Return on Assets (TTM)-71.29%-18.31%Madrigal
Free Cash Flow (TTM)$-201.05M$-462.03MScholar Rock Holding
1-Year Return374.26%115.75%Scholar Rock Holding
Price-to-Sales Ratio (TTM)N/A19.16N/A
Enterprise Value$3.45B$9.20BMadrigal
EV/Revenue RatioN/A17.85N/A
Gross Profit Margin (TTM)N/A95.74%N/A
Revenue per Share (TTM)$0$23Madrigal
Earnings per Share (Diluted)$-2.89$-13.20Scholar Rock Holding
Beta (Stock Volatility)0.37-1.03Madrigal
Performance
News Sentiment
Key Stats
Valuation
Financials
Short Interest
Dividends

Scholar Rock Holding vs Madrigal Stock Performance Analysis

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Scholar Rock Holding
Madrigal
Scholar Rock Holding Stock Overview | Madrigal Stock Overview

Performance Comparison

Short-term Returns

Stock1D1W1M3M6MYTD
Scholar Rock Holding1.47%2.03%6.25%-1.01%8.14%-20.31%
Madrigal0.11%6.30%3.10%49.81%34.38%43.30%

Long-term Returns

Stock1Y3Y5Y10Y15Y20Y
Scholar Rock Holding374.26%354.65%136.97%134.60%134.60%134.60%
Madrigal115.75%499.28%247.00%552.12%224.42%30.42%

News Based Sentiment: Scholar Rock Holding vs Madrigal

Scholar Rock Holding

News based Sentiment: NEGATIVE

The significant stock decline and reduced trading volume on October 1, 2025, represent a noteworthy negative event for Scholar Rock investors. The sharp drop and lack of buying interest raise concerns about the company's near-term prospects and investor confidence.

View Scholar Rock Holding News Sentiment Analysis

Madrigal

News based Sentiment: POSITIVE

September was a strong month for Madrigal, marked by impressive Q2 sales of Rezdiffra, positive analyst ratings (including a $523 price target from UBS), and continued institutional investment. While the company is not yet profitable, the momentum in sales and market adoption suggests a positive trajectory for future growth.

View Madrigal News Sentiment Analysis

Performance & Financial Health Analysis: Scholar Rock Holding vs Madrigal

MetricSRRKMDGL
Market Information
Market Cap i$3.62B$9.88B
Market Cap CategoryMid capMid cap
10 Day Avg. Volume i3,507,920332,800
90 Day Avg. Volume i2,438,970366,657
Last Close$35.19$449.64
52 Week Range$6.76 - $46.98$200.63 - $463.63
% from 52W High-25.10%-3.02%
All-Time High$70.00 (Mar 15, 2021)$463.62 (Oct 01, 2025)
% from All-Time High-49.73%-3.02%
Growth Metrics
Quarterly Revenue GrowthN/A13.54%
Quarterly Earnings GrowthN/A13.54%
Financial Health
Profit Margin (TTM) i0.00%-0.55%
Operating Margin (TTM) i0.00%-0.22%
Return on Equity (TTM) i-1.72%-0.36%
Debt to Equity (MRQ) i26.3717.81
Cash & Liquidity
Book Value per Share (MRQ)$2.43$31.32
Cash per Share (MRQ)$3.07$35.76
Operating Cash Flow (TTM) i$-257,584,000$-307,412,992
Levered Free Cash Flow (TTM) i$-142,852,992$-219,782,000
Dividends
Last 12-Month Dividend Yield iN/AN/A
Last 12-Month Dividend iN/AN/A

Valuation & Enterprise Metrics Analysis: Scholar Rock Holding vs Madrigal

MetricSRRKMDGL
Price Ratios
P/E Ratio (TTM) i-15.08-20.87
Forward P/E i-17.84-31.74
PEG Ratio i-0.240.28
Price to Sales (TTM) iN/A19.16
Price to Book (MRQ) i15.7914.15
Market Capitalization
Market Capitalization i$3.62B$9.88B
Enterprise Value i$3.45B$9.20B
Enterprise Value Metrics
Enterprise to Revenue iN/A17.85
Enterprise to EBITDA i-10.74-29.84
Risk & Other Metrics
Beta i0.37-1.03
Book Value per Share (MRQ) i$2.43$31.32

Financial Statements Comparison: Scholar Rock Holding vs Madrigal

Financial Metrics

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Revenue

EBITDA

Shareholders Equity

Operating Margin

Free Cash Flow

Long Term Debt

Profit Margin

Current Ratio

Operating Cash Flow

Income Statement (MRQ)

Metric (MRQ)SRRKMDGL
Revenue/Sales i$0$137.25M
Cost of Goods Sold iN/A$4.51M
Gross Profit iN/A$132.74M
Research & Development i$62.40M$44.17M
Operating Income (EBIT) i$-112.11M$-79.31M
EBITDA i$-108.41M$-69.56M
Pre-Tax Income i$-110.03M$-73.24M
Income Tax iN/AN/A
Net Income (Profit) i$-110.03M$-73.24M

Balance Sheet & Liquidity Metrics (MRQ)

Metric (MRQ)SRRKMDGL
Cash & Equivalents i$137.93M$183.65M
Total Current Assets i$385.25M$987.98M
Total Current Liabilities i$37.57M$167.24M
Long-Term Debt i$57.65M$118.76M
Total Shareholders Equity i$312.33M$710.64M
Retained Earnings i$-997.44M$-1.88B
Property, Plant & Equipment i$17.04M$4.01M

Cash Flow Statement Comparison (MRQ)

Metric (MRQ)SRRKMDGL
Operating Cash Flow i$-66.36M$-81.76M
Capital Expenditures i$-271,000$0
Free Cash Flow i$-78.95M$-88.89M
Debt Repayment i$-25.52MN/A
Common Stock Repurchase iN/AN/A

Short Interest & Institutional Ownership Analysis

MetricSRRKMDGL
Shares Short i16.08M4.14M
Short Ratio i8.4710.95
Short % of Float i0.29%0.22%
Average Daily Volume (10 Day) i3,507,920332,800
Average Daily Volume (90 Day) i2,438,970366,657
Shares Outstanding i93.82M22.00M
Float Shares i80.34M10.98M
% Held by Insiders i0.04%0.08%
% Held by Institutions i1.21%1.08%

Dividend Analysis & Yield Comparison: Scholar Rock Holding vs Madrigal

MetricSRRKMDGL
Last 12-Month Dividend iN/AN/A
Last 12-Month Dividend Yield iN/AN/A
3-Year Avg Annual Dividend iN/AN/A
3-Year Avg Dividend Yield iN/AN/A
3-Year Total Dividends iN/AN/A
Ex-Dividend DateN/AN/A