Twist Bioscience [TWST] vs Danaher [DHR] Detailed Stock Comparison

Twist Bioscience Corporation

NASDAQ
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Danaher Corporation

NYSE
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TLDR: Quick Comparison Summary

Based on 21 vital metrics comparison: Twist Bioscience Corporation wins in 2 metrics, Danaher Corporation wins in 17 metrics, with 0 ties. Danaher Corporation appears stronger overall.

View Metrics Details

Vital Metrics Comparison

Metric Twist Bioscience Corporation Danaher Corporation Better
P/E Ratio (TTM) -45.26 34.61 Danaher Corporation
Price-to-Book Ratio 8.49 2.40 Danaher Corporation
Debt-to-Equity Ratio 24.79 37.17 Twist Bioscience Corporation
PEG Ratio 8.00 3.84 Danaher Corporation
EV/EBITDA -33.62 17.69 Danaher Corporation
Profit Margin (TTM) -19.56% 14.89% Danaher Corporation
Operating Margin (TTM) -31.73% 22.94% Danaher Corporation
EBITDA Margin (TTM) N/A 22.94% N/A
Return on Equity -16.79% 7.08% Danaher Corporation
Return on Assets (TTM) -13.49% 4.19% Danaher Corporation
Free Cash Flow (TTM) $-75.63M $5.26B Danaher Corporation
Dividend Yield N/A 0.56% N/A
1-Year Return 127.24% -10.25% Twist Bioscience Corporation
Price-to-Sales Ratio (TTM) 9.90 5.10 Danaher Corporation
Enterprise Value $3.79B $140.38B Danaher Corporation
EV/Revenue Ratio 9.68 5.67 Danaher Corporation
Gross Profit Margin (TTM) 52.05% 60.34% Danaher Corporation
Revenue per Share (TTM) $7 $35 Danaher Corporation
Earnings per Share (Diluted) $-1.27 $5.16 Danaher Corporation
Beta (Stock Volatility) 2.21 0.99 Danaher Corporation
Short % of Float 29.74% 1.10% Danaher Corporation

Twist Bioscience Corporation vs Danaher Corporation Stock Performance Analysis

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TWST
DHR

Performance Comparison

Short-term Returns

Stock1D1W1M3M6MYTD
Twist Bioscience Corporation6.07%15.35%64.31%79.49%160.03%149.43%
Danaher Corporation0.56%-1.32%11.85%-5.38%-20.75%-21.40%

Long-term Returns

Stock1Y3Y5Y10Y15Y20Y
Twist Bioscience Corporation127.24%316.00%-31.53%444.07%444.07%444.07%
Danaher Corporation-10.25%-15.98%-20.94%174.08%416.93%738.84%

Performance & Financial Health Analysis: Twist Bioscience Corporation vs Danaher Corporation

MetricTWSTDHR
Market Information
Market Cap i$3.61B$126.39B
Market Cap CategoryMid capLarge cap
10 Day Avg. Volume i1,422,1845,174,666
90 Day Avg. Volume i1,214,5614,357,215
Last Close$80.79$181.10
52 Week Range$23.30 - $82.99$160.93 - $242.80
% from 52W High-2.65%-25.41%
All-Time High$214.07 (Jan 18, 2021)$296.06 (Sep 06, 2021)
% from All-Time High-62.26%-38.83%
Growth Metrics
Quarterly Revenue Growth0.17%0.04%
Quarterly Earnings Growth0.17%0.08%
Financial Health
Profit Margin (TTM) i-0.20%0.15%
Operating Margin (TTM) i-0.32%0.23%
Return on Equity (TTM) i-0.17%0.07%
Debt to Equity (MRQ) i24.7937.17
Cash & Liquidity
Book Value per Share (MRQ)$7.44$74.32
Cash per Share (MRQ)$3.23$8.06
Operating Cash Flow (TTM) i$-51,014,000$6.44B
Levered Free Cash Flow (TTM) i$-47,241,876$4.57B
Dividends
Last 12-Month Dividend Yield iN/A0.56%
Last 12-Month Dividend iN/A$1.28

Valuation & Enterprise Metrics Analysis: Twist Bioscience Corporation vs Danaher Corporation

MetricTWST (Apr 24, 2026)DHR (Apr 24, 2026)
Price Ratios
P/E Ratio (TTM) i-45.2634.61
Forward P/E i-33.5319.64
PEG Ratio i8.003.84
Price to Sales (TTM) i9.905.10
Price to Book (MRQ) i8.492.40
Market Capitalization
Market Capitalization i$3.61B$126.39B
Enterprise Value i$3.79B$140.38B
Enterprise Value Metrics
Enterprise to Revenue i9.685.67
Enterprise to EBITDA i-33.6217.69
Risk & Other Metrics
Beta i2.210.99
Book Value per Share (MRQ) i$7.44$74.32

Financial Statements Comparison: Twist Bioscience Corporation vs Danaher Corporation

Financial Metrics

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Revenue

Operating Margin

Profit Margin

Long Term Debt

Income Flow Analysis

Financial Statements Comparison

Income Statement

MetricTWST (2025)DHR (2025)
Revenue/Sales i376.57M24.57B
Cost of Goods Sold i185.57M10.05B
COGS % of Revenue i49.3%40.9%
Gross Profit i191.00M14.52B
Gross Margin i50.7%59.1%
Research & Development i80.29M1.60B
Operating Income (EBIT) i-136.26M4.69B
Operating Margin i-36.2%19.1%
EBITDA i-160.25M7.17B
EBITDA Margin i-42.6%29.2%
Pre-Tax Income i-76.95M4.23B
Pre-Tax Income % of Revenue i-20.4%17.2%
Income Tax i719,000633.00M
Income Tax % of Revenue i0.2%2.6%
Net Income (Profit) i-77.67M3.61B
Profit Margin i-20.6%14.7%

Balance Sheet & Liquidity Metrics

MetricTWST (2025)DHR (2025)
Cash & Equivalents i183.05M4.62B
Total Current Assets i332.97M12.76B
Total Current Assets % of Revenue i88.4%51.9%
Total Current Liabilities i91.41M6.81B
Total Current Liabilities % of Revenue i24.3%27.7%
Long-Term Debt i61.75M19.50B
Long-Term Debt % of Revenue i16.4%79.4%
Total Shareholders Equity i472.96M52.54B
Retained Earnings i-1.32B46.89B
Retained Earnings % of Revenue i-350.4%190.9%
Property, Plant & Equipment i150.96M2.14B

Cash Flow Statement Comparison

MetricTWST (2025)DHR (2025)
Operating Cash Flow i1.59M5.64B
Operating Cash Flow % of Revenue i0.4%23.0%
Capital Expenditures i-28.00M-1.12B
Free Cash Flow i-75.63M5.26B
FCF Margin i-20.1%21.4%
Debt Repayment iN/A-500.00M
Common Stock Repurchase i-16,000-3.09B

Short Interest & Institutional Ownership Analysis

MetricTWSTDHR
Shares Short i14.15M6.94M
Short Ratio i13.071.68
Short % of Float i29.74%1.10%
Shares Outstanding i61.27M707.70M
Float Shares i54.55M630.65M
% Held by Insiders i1.50%10.78%
% Held by Institutions i122.49%85.08%
% Held by Public i-23.99%4.14%

Dividend Analysis & Yield Comparison: Twist Bioscience Corporation vs Danaher Corporation

MetricTWSTDHR
Last 12-Month Dividend iN/A$1.28
Last 12-Month Dividend Yield iN/A0.56%
3-Year Avg Annual Dividend iN/A$10.51
3-Year Avg Dividend Yield iN/A1.11%
3-Year Total Dividends iN/A$31.54
Ex-Dividend DateN/ADec 26, 2025