Inspire Medical [INSP] vs Axogen [AXGN] Detailed Stock Comparison

Inspire Medical Systems, Inc.

NYSE
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Axogen Inc.

NASDAQ
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TLDR: Quick Comparison Summary

Based on 20 vital metrics comparison: Inspire Medical Systems, Inc. wins in 15 metrics, Axogen Inc. wins in 3 metrics, with 1 ties. Inspire Medical Systems, Inc. appears stronger overall.

View Metrics Details

Vital Metrics Comparison

Metric Inspire Medical Systems, Inc. Axogen Inc. Better
P/E Ratio (TTM) 10.64 -110.18 Inspire Medical Systems, Inc.
Price-to-Book Ratio 1.90 13.15 Inspire Medical Systems, Inc.
Debt-to-Equity Ratio 4.12 55.50 Inspire Medical Systems, Inc.
PEG Ratio 0.04 0.04 Tie
EV/EBITDA 18.66 -2,165.44 Inspire Medical Systems, Inc.
Profit Margin (TTM) 15.95% -6.97% Inspire Medical Systems, Inc.
Operating Margin (TTM) 17.14% -16.31% Inspire Medical Systems, Inc.
EBITDA Margin (TTM) 17.14% N/A N/A
Return on Equity 19.77% -13.49% Inspire Medical Systems, Inc.
Return on Assets (TTM) 3.71% -2.31% Inspire Medical Systems, Inc.
Free Cash Flow (TTM) $78.48M $-4.78M Inspire Medical Systems, Inc.
1-Year Return -70.07% 262.53% Axogen Inc.
Price-to-Sales Ratio (TTM) 1.64 8.27 Inspire Medical Systems, Inc.
Enterprise Value $1.21B $1.89B Axogen Inc.
EV/Revenue Ratio 1.33 8.40 Inspire Medical Systems, Inc.
Gross Profit Margin (TTM) 86.59% 74.13% Inspire Medical Systems, Inc.
Revenue per Share (TTM) $31 $5 Inspire Medical Systems, Inc.
Earnings per Share (Diluted) $4.89 $-0.34 Inspire Medical Systems, Inc.
Beta (Stock Volatility) 0.86 0.98 Inspire Medical Systems, Inc.
Short % of Float 14.57% 6.92% Axogen Inc.

Inspire Medical Systems, Inc. vs Axogen Inc. Stock Performance Analysis

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INSP
AXGN

Performance Comparison

Short-term Returns

Stock1D1W1M3M6MYTD
Inspire Medical Systems, Inc.-0.35%-4.22%-26.26%-38.54%-69.99%-56.17%
Axogen Inc.2.97%1.91%-4.69%36.21%43.42%31.06%

Long-term Returns

Stock1Y3Y5Y10Y15Y20Y
Inspire Medical Systems, Inc.-70.07%-86.64%-74.92%69.02%69.02%69.02%
Axogen Inc.262.53%346.61%108.01%590.21%1,114.77%9,770.00%

Performance & Financial Health Analysis: Inspire Medical Systems, Inc. vs Axogen Inc.

MetricINSPAXGN
Market Information
Market Cap i$1.62B$1.94B
Market Cap CategorySmall capSmall cap
10 Day Avg. Volume i951,3771,245,238
90 Day Avg. Volume i976,5861,068,353
Last Close$40.44$40.63
52 Week Range$38.91 - $147.03$9.22 - $45.83
% from 52W High-72.50%-11.35%
All-Time High$330.00 (Jul 10, 2023)$56.85 (Jul 23, 2018)
% from All-Time High-87.75%-28.53%
Growth Metrics
Quarterly Revenue Growth0.12%0.21%
Quarterly Earnings Growth2.86%0.21%
Financial Health
Profit Margin (TTM) i0.16%-0.07%
Operating Margin (TTM) i0.17%-0.16%
Return on Equity (TTM) i0.20%-0.13%
Debt to Equity (MRQ) i4.1255.50
Cash & Liquidity
Book Value per Share (MRQ)$27.33$2.73
Cash per Share (MRQ)$10.78$0.80
Operating Cash Flow (TTM) i$116.98M$812,000
Levered Free Cash Flow (TTM) i$54.50M$3.58M
Dividends
Last 12-Month Dividend Yield iN/AN/A
Last 12-Month Dividend iN/A$0.00

Valuation & Enterprise Metrics Analysis: Inspire Medical Systems, Inc. vs Axogen Inc.

MetricINSP (Apr 24, 2026)AXGN (Apr 24, 2026)
Price Ratios
P/E Ratio (TTM) i10.64-110.18
Forward P/E i20.1347.31
PEG Ratio i0.040.04
Price to Sales (TTM) i1.648.27
Price to Book (MRQ) i1.9013.15
Market Capitalization
Market Capitalization i$1.62B$1.94B
Enterprise Value i$1.21B$1.89B
Enterprise Value Metrics
Enterprise to Revenue i1.338.40
Enterprise to EBITDA i18.66-2,165.44
Risk & Other Metrics
Beta i0.860.98
Book Value per Share (MRQ) i$27.33$2.73

Financial Statements Comparison: Inspire Medical Systems, Inc. vs Axogen Inc.

Financial Metrics

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Revenue

Operating Margin

Profit Margin

Long Term Debt

Income Flow Analysis

Financial Statements Comparison

Income Statement

MetricINSP (2025)AXGN (2025)
Revenue/Sales i911.98M225.21M
Cost of Goods Sold i133.23M57.86M
COGS % of Revenue i14.6%25.7%
Gross Profit i778.76M167.35M
Gross Margin i85.4%74.3%
Research & Development i103.17M32.89M
Operating Income (EBIT) i50.95M-7.85M
Operating Margin i5.6%-3.5%
EBITDA i79.79M826,000
EBITDA Margin i8.7%0.4%
Pre-Tax Income i65.70M-15.70M
Pre-Tax Income % of Revenue i7.2%-7.0%
Income Tax i-79.73MN/A
Income Tax % of Revenue i-8.7%0.0%
Net Income (Profit) i145.42M-15.70M
Profit Margin i15.9%-7.0%

Balance Sheet & Liquidity Metrics

MetricINSP (2025)AXGN (2025)
Cash & Equivalents i104.81M35.55M
Total Current Assets i583.65M120.42M
Total Current Assets % of Revenue i64.0%53.5%
Total Current Liabilities i96.06M23.56M
Total Current Liabilities % of Revenue i10.5%10.5%
Long-Term Debt i30.00M65.26M
Long-Term Debt % of Revenue i3.3%29.0%
Total Shareholders Equity i781.16M128.85M
Retained Earnings i-146.49M-306.96M
Retained Earnings % of Revenue i-16.1%-136.3%
Property, Plant & Equipment i54.21M29.38M

Cash Flow Statement Comparison

MetricINSP (2025)AXGN (2025)
Operating Cash Flow i107.85M10.26M
Operating Cash Flow % of Revenue i11.8%4.6%
Capital Expenditures i-38.50M-3.75M
Free Cash Flow i78.48M-4.78M
FCF Margin i8.6%-2.1%
Debt Repayment iN/A-32,000
Common Stock Repurchase i-175.02MN/A

Short Interest & Institutional Ownership Analysis

MetricINSPAXGN
Shares Short i3.20M3.50M
Short Ratio i3.374.04
Short % of Float i14.57%6.92%
Shares Outstanding i28.58M47.20M
Float Shares i26.71M50.75M
% Held by Insiders i1.17%2.12%
% Held by Institutions i121.08%88.11%
% Held by Public i-22.25%9.77%

Dividend Analysis & Yield Comparison: Inspire Medical Systems, Inc. vs Axogen Inc.

MetricINSPAXGN
Last 12-Month Dividend iN/A$0.00
Last 12-Month Dividend Yield iN/AN/A
3-Year Avg Annual Dividend iN/A$0.00
3-Year Avg Dividend Yield iN/AN/A
3-Year Total Dividends iN/A$0.00
Ex-Dividend DateN/AN/A