Amicus Therapeutics (FOLD) | Financial Analysis & Statements
Amicus Therapeutics Inc. Mid-cap Healthcare
TL;DR: Financial Overview - Revenue, Profits & Key Metrics
Latest Quarterly: Dec 2025Income Metrics
Revenue
185.2M
Gross Profit
158.7M
85.67%
Operating Income
15.9M
8.61%
Net Income
1.7M
0.91%
Balance Sheet Metrics
Total Assets
949.9M
Total Liabilities
675.6M
Shareholders Equity
274.2M
Debt to Equity
2.46
Cash Flow Metrics
Operating Cash Flow
21.6M
Free Cash Flow
16.0M
Revenue & Profitability Trend
Quarter Income Flow
Dec 31, 2025
Annual Income Flow
2025
Amicus Therapeutics Income Statement From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Revenue | 634.2M | 528.3M | 399.4M | 329.2M | 305.5M |
| Cost of Goods Sold | 72.9M | 52.9M | 37.3M | 38.6M | 34.5M |
| Gross Profit | 561.3M | 475.4M | 362.0M | 290.6M | 271.0M |
| Gross Margin % | 88.5% | 90.0% | 90.7% | 88.3% | 88.7% |
| Operating Expenses | |||||
| Research & Development | 135.8M | 109.4M | 152.4M | 276.7M | 272.0M |
| Selling, General & Administrative | 383.5M | 323.4M | 275.3M | 213.0M | 192.7M |
| Other Operating Expenses | - | - | - | - | - |
| Total Operating Expenses | 519.3M | 432.7M | 427.7M | 489.7M | 464.8M |
| Operating Income | 34.5M | 34.1M | -73.5M | -204.4M | -199.9M |
| Operating Margin % | 5.4% | 6.4% | -18.4% | -62.1% | -65.4% |
| Non-Operating Items | |||||
| Interest Income | 3.3M | 5.4M | 7.1M | 3.0M | 509.0K |
| Interest Expense | 46.2M | 49.6M | 50.1M | 37.1M | 32.5M |
| Other Non-Operating Income | 8.5M | -18.6M | -33.5M | -3.5M | -9.7M |
| Pre-tax Income | 191.0K | -28.8M | -150.1M | -242.0M | -241.6M |
| Income Tax | 27.3M | 27.4M | 1.5M | -5.5M | 8.9M |
| Effective Tax Rate % | 14,293.7% | 0.0% | 0.0% | 0.0% | 0.0% |
| Net Income | -27.1M | -56.1M | -151.6M | -236.6M | -250.5M |
| Net Margin % | -4.3% | -10.6% | -38.0% | -71.9% | -82.0% |
| Key Metrics | |||||
| EBITDA | 55.5M | 38.6M | -74.4M | -191.9M | -196.1M |
| EPS (Basic) | - | $-0.18 | $-0.51 | $-0.82 | $-0.92 |
| EPS (Diluted) | - | $-0.18 | $-0.51 | $-0.82 | $-0.92 |
| Basic Shares Outstanding | - | 304380502 | 295164515 | 289057198 | 271421986 |
| Diluted Shares Outstanding | - | 304380502 | 295164515 | 289057198 | 271421986 |
Income Statement Trend
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Amicus Therapeutics Balance Sheet From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Assets | |||||
| Current Assets | |||||
| Cash & Equivalents | 214.0M | 213.8M | 247.0M | 148.8M | 245.2M |
| Short-term Investments | 79.5M | 36.2M | 39.2M | 144.8M | 237.3M |
| Accounts Receivable | 115.3M | 101.1M | 87.6M | 66.2M | 52.7M |
| Inventory | 228.8M | 118.8M | 59.7M | 23.8M | 26.8M |
| Other Current Assets | 38.5M | 34.9M | 49.5M | 40.2M | 34.8M |
| Total Current Assets | 676.2M | 504.7M | 483.1M | 423.8M | 596.8M |
| Non-Current Assets | |||||
| Property, Plant & Equipment | 36.9M | 38.5M | 42.5M | 45.9M | 37.2M |
| Goodwill | 409.5M | 412.8M | 416.1M | 418.6M | 418.6M |
| Intangible Assets | 13.9M | 17.2M | 20.5M | 23.0M | 23.0M |
| Long-term Investments | - | - | - | - | - |
| Other Non-Current Assets | 13.7M | 13.6M | 18.6M | 19.2M | 24.4M |
| Total Non-Current Assets | 273.7M | 280.3M | 294.8M | 300.4M | 308.3M |
| Total Assets | 949.9M | 785.0M | 777.9M | 724.2M | 905.1M |
| Liabilities | |||||
| Current Liabilities | |||||
| Accounts Payable | 28.6M | 12.9M | 15.1M | 15.4M | 21.5M |
| Short-term Debt | 8.7M | 8.5M | 8.3M | 8.6M | 7.4M |
| Current Portion of Long-term Debt | - | - | - | - | - |
| Other Current Liabilities | 11.7M | 8.7M | 10.4M | 7.5M | 4.2M |
| Total Current Liabilities | 237.8M | 148.7M | 167.7M | 139.0M | 146.0M |
| Non-Current Liabilities | |||||
| Long-term Debt | 433.6M | 435.2M | 436.7M | 443.6M | 432.7M |
| Deferred Tax Liabilities | - | - | - | 4.9M | 4.9M |
| Other Non-Current Liabilities | 4.2M | 7.1M | 13.3M | 18.5M | 8.2M |
| Total Non-Current Liabilities | 437.8M | 442.3M | 450.0M | 462.1M | 451.8M |
| Total Liabilities | 675.6M | 591.0M | 617.7M | 601.1M | 597.8M |
| Equity | |||||
| Common Stock | 3.0M | 2.9M | 2.9M | 2.8M | 2.8M |
| Retained Earnings | -2.8B | -2.7B | -2.7B | -2.5B | -2.3B |
| Treasury Stock | 71.0K | - | - | - | - |
| Other Equity | - | - | - | - | - |
| Total Shareholders Equity | 274.2M | 194.0M | 160.2M | 123.0M | 307.4M |
| Key Metrics | |||||
| Total Debt | 442.4M | 443.6M | 445.1M | 452.1M | 440.1M |
| Working Capital | 438.3M | 356.0M | 315.4M | 284.8M | 450.9M |
Balance Sheet Composition
Amicus Therapeutics Cash Flow Statement From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Operating Activities | |||||
| Net Income | -27.1M | -56.1M | -151.6M | -236.6M | -250.5M |
| Depreciation & Amortization | 7.5M | 8.5M | 7.9M | 5.3M | 6.2M |
| Stock-Based Compensation | 87.4M | 84.9M | 86.1M | 76.5M | 57.8M |
| Working Capital Changes | -38.3M | -112.9M | -18.6M | -33.7M | -12.7M |
| Operating Cash Flow | 32.1M | -73.3M | -97.3M | -184.7M | -200.4M |
| Investing Activities | |||||
| Capital Expenditures | - | - | - | - | - |
| Acquisitions | - | - | - | - | - |
| Investment Purchases | -94.4M | -114.8M | -91.7M | -243.3M | -341.4M |
| Investment Sales | 51.3M | 117.8M | 197.2M | 335.9M | 424.0M |
| Investing Cash Flow | -43.1M | 3.0M | 105.5M | 96.1M | 82.6M |
| Financing Activities | |||||
| Share Repurchases | - | - | - | - | - |
| Dividends Paid | - | - | - | - | - |
| Debt Issuance | 0 | 0 | 387.4M | 0 | 0 |
| Debt Repayment | -272.0K | -97.0K | -408.3M | -283.0K | -479.0K |
| Financing Cash Flow | -18.6M | -2.6M | 51.4M | -11.8M | 182.6M |
| Free Cash Flow | 29.8M | -37.4M | -76.5M | -170.3M | -206.4M |
| Net Change in Cash | -29.7M | -72.9M | 59.6M | -100.4M | 64.9M |
Cash Flow Trend
Amicus Therapeutics Key Financial Ratios
Valuation Ratios
Forward P/E
17.66
Price to Book
16.40
Price to Sales
7.16
PEG Ratio
17.66
Profitability Ratios
Profit Margin
-4.28%
Operating Margin
8.61%
Return on Equity
-11.58%
Return on Assets
2.49%
Financial Health
Current Ratio
2.84
Debt to Equity
161.30
Beta
0.48
Per Share Data
EPS (TTM)
$-0.09
Book Value per Share
$0.88
Revenue per Share
$2.06
Peer Financial Comparison
| Company | Market Cap | P/E Ratio | P/B Ratio | ROE | Profit Margin | Debt/Equity |
|---|---|---|---|---|---|---|
| FOLD | 4.5B | - | 16.40 | -11.58% | -4.28% | 161.30 |
| Vertex | 109.4B | 28.40 | 5.92 | 22.54% | 32.94% | 10.91 |
| Regeneron | 81.0B | 18.00 | 2.45 | 14.86% | 31.41% | 9.51 |
| Axsome Therapeutics | 9.5B | -50.54 | 105.31 | -252.12% | -28.69% | 247.03 |
| Praxis Precision | 9.6B | - | 9.46 | -45.83% | 0.00% | 0.01 |
| Bio-Techne | 9.1B | 117.16 | 4.55 | 3.80% | 6.41% | 20.07 |
Financial data is updated regularly. All figures are in the company's reporting currency.






