Iovance Biotherapeutics, Inc. | Small-cap | Healthcare

Iovance Performance Comparison

Loading chart data...

Stock Range

Today's Range

Low: $2.45 High: $2.71
on August 1, 2025

52 Week Range

Low: $1.64 High: $12.51
on May 19, 2025
on November 7, 2024

All-Time High: $165.00 on June 6, 2011

Explore how other US stocks compare to their 52-week ranges: View US Market 52-Week Insights

Key Statistics

Market Cap i $894.9M
EPS i -1.22
P/E Ratio (TTM) i -2.09
Forward P/E i -3.27
P/B Ratio i 1.17
PEG Ratio i -3.27
Div. Yield i N/A
ROE i -51.85%
Beta i 0.852
Debt to Equity i 7.00

Financial Highlights

Profitability

Gross Margin i -0.85%
Operating Margin i -245.77%
Profit Margin i -176.49%

Returns and Earnings

Return on Assets (TTM) i -27.14%
Return on Equity (TTM) i -51.85%
EBITDA i $-365.0M
Net Income (TTM) i $-375.4M

Growth

Revenue (TTM) i
Revenue Per Share (TTM) i $0.70
Quarterly Revenue Growth (YoY) i 6,798.50%
Quarterly Earnings Growth (YoY) i 6,798.46%

Peer Performance Comparison

Performance comparison table showing returns for peer companies over various time periods
CompanyMarket Cap1W1M3M6MYTD1Y3Y5Y
Iovance IOVA 894.94M Small-cap-14.38%54.02%-19.52%-52.48%-65.60%-65.60%-78.00%-90.83%
Vertex VRTX 118.67B Large-cap-1.60%2.20%-7.36%-1.75%13.89%-6.54%60.45%69.28%
Regeneron REGN 58.89B Large-cap-0.75%4.48%-5.28%-16.19%-21.86%-48.36%-8.92%-9.89%
Harmony Biosciences HRMY 1.98B Small-cap-8.32%7.40%15.20%-11.75%-1.23%6.17%-34.48%-4.44%
Denali Therapeutics DNLI 1.95B Small-cap-1.68%-3.66%-16.31%-38.46%-35.51%-38.55%-62.41%-57.48%
Amicus Therapeutics FOLD 1.95B Small-cap4.29%8.22%-5.39%-34.44%-32.12%-37.30%-48.11%-58.99%

Ownership & Short Interest

Insider Ownership i 0.37%
Institutional Ownership i 80.63%
Shares Short i 99M
Short Ratio i 8.04
Short % of Shares Outstanding i 32.35%
Average 10-Day Volume i 34M
Average 90-Day Volume i 21M

Iovance Recurring Investment / Dollar-Cost Averaging Calculator

Calculate how a regular investment in Iovance would have performed over time.

$
If not specified, the latest available data will be used

Note: This calculator is for informational purposes only and does not consider taxes, fees, or other costs associated with investing.

Frequently Asked Questions

In the last 52 weeks, Iovance reached a high of $12.51 (on November 7, 2024) and a low of $1.64 (on May 19, 2025).
Curious about Iovance's size and valuation? Its market capitalization stands at 894.94M. When it comes to valuation, the P/E ratio (trailing twelve months) is -2.09, and the forward P/E (looking ahead) is -3.27.
As for dividends, Iovance isn't currently offering a significant yield, or that specific data isn't available right now.

When looking at Iovance, it can be helpful to see how it compares to other players in its field. Here are a few similar companies or key competitors:

CompanyMkt CapSectorIndustry1Y Return3Y Return
Vertex
VRTX
118.67BHealthcareBiotechnology-6.54%60.45%
Regeneron
REGN
58.89BHealthcareBiotechnology-48.36%-8.92%
Harmony Biosciences
HRMY
1.98BHealthcareBiotechnology6.17%-34.48%
Denali Therapeutics
DNLI
1.95BHealthcareBiotechnology-38.55%-62.41%
Amicus Therapeutics
FOLD
1.95BHealthcareBiotechnology-37.30%-48.11%

For a more comprehensive list, please see the Peer Performance Comparison table on this page.

To get a sense of Iovance's financial health, here are a few key indicators: its Return on Equity (ROE) over the last twelve months is -51.85%, the Debt to Equity ratio from the most recent quarter is 7.00, and its Gross Profit Margin stands at -0.85%.
Looking at Iovance's growth, its revenue over the trailing twelve months (TTM) was $213M. Compared to the same quarter last year (YoY), quarterly revenue grew by 6,798.50%, and quarterly earnings saw a YoY growth of 6,798.46%.
Wondering who owns Iovance stock? Company insiders (like executives and directors) hold about 0.37% of the shares, while institutional investors (such as mutual funds and pension funds) own approximately 80.63%.

For more common questions about our data, please visit our About Data page.

Data is provided for informational purposes only. Devyara does not guarantee the accuracy of the data displayed.