Vertex Pharmaceuticals Inc. | Large-cap | Healthcare

Vertex Performance Comparison

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Stock Range

Today's Range

Low: $388.71 High: $395.76
on August 15, 2025

52 Week Range

Low: $362.50 High: $519.88
on August 11, 2025
on November 8, 2024

All-Time High: $519.88 on November 4, 2024

Explore how other US stocks compare to their 52-week ranges: View US Market 52-Week Insights

Key Statistics

Market Cap i $100.4B
EPS i 14.06
P/E Ratio (TTM) i 27.85
Forward P/E i 20.86
P/B Ratio i 5.84
PEG Ratio i -0.22
Div. Yield i N/A
ROE i 22.77%
Beta i 0.444
Debt to Equity i 8.89

Financial Highlights

Profitability

Gross Margin i 86.25%
Operating Margin i 38.93%
Profit Margin i 31.86%

Returns and Earnings

Return on Assets (TTM) i 13.09%
Return on Equity (TTM) i 22.77%
EBITDA i $485.8M
Net Income (TTM) i $3.6B

Growth

Revenue (TTM) i
Revenue Per Share (TTM) i $44.44
Quarterly Revenue Growth (YoY) i 12.10%
Quarterly Earnings Growth (YoY) i 12.06%

Peer Performance Comparison

Performance comparison table showing returns for peer companies over various time periods
CompanyMarket Cap1W1M3M6MYTD1Y3Y5Y
Vertex VRTX 100.38B Large-cap7.15%-15.40%-9.59%-15.01%-3.21%-17.72%31.35%44.79%
Regeneron REGN 58.99B Large-cap3.09%5.92%-0.78%-14.65%-18.85%-50.78%-6.14%-4.14%
Alnylam ALNY 56.35B Large-cap2.27%44.29%58.40%79.56%92.15%67.35%107.86%228.63%
Insmed INSM 25.79B Large-cap16.66%24.23%90.12%57.08%82.70%67.72%408.56%370.89%
Royalty Pharma plc RPRX 21.26B Large-cap-3.27%-0.44%9.75%10.65%40.95%33.79%-17.57%-13.39%
Incyte INCY 15.94B Large-cap10.88%27.36%38.50%21.96%25.01%39.83%16.61%-7.64%

Ownership & Short Interest

Insider Ownership i 0.14%
Institutional Ownership i 99.81%
Shares Short i 4M
Short Ratio i 4.04
Short % of Shares Outstanding i 1.92%
Average 10-Day Volume i 3M
Average 90-Day Volume i 2M

Vertex Recurring Investment / Dollar-Cost Averaging Calculator

Calculate how a regular investment in Vertex would have performed over time.

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Frequently Asked Questions

In the last 52 weeks, Vertex reached a high of $519.88 (on November 8, 2024) and a low of $362.50 (on August 11, 2025).
Curious about Vertex's size and valuation? Its market capitalization stands at 100.38B. When it comes to valuation, the P/E ratio (trailing twelve months) is 27.85, and the forward P/E (looking ahead) is 20.86.
As for dividends, Vertex isn't currently offering a significant yield, or that specific data isn't available right now.

When looking at Vertex, it can be helpful to see how it compares to other players in its field. Here are a few similar companies or key competitors:

CompanyMkt CapSectorIndustry1Y Return3Y Return
Regeneron
REGN
58.99BHealthcareBiotechnology-50.78%-6.14%
Alnylam
ALNY
56.35BHealthcareBiotechnology67.35%107.86%
Insmed
INSM
25.79BHealthcareBiotechnology67.72%408.56%
Royalty Pharma plc
RPRX
21.26BHealthcareBiotechnology33.79%-17.57%
Incyte
INCY
15.94BHealthcareBiotechnology39.83%16.61%

For a more comprehensive list, please see the Peer Performance Comparison table on this page.

To get a sense of Vertex's financial health, here are a few key indicators: its Return on Equity (ROE) over the last twelve months is 22.77%, the Debt to Equity ratio from the most recent quarter is 8.89, and its Gross Profit Margin stands at 86.25%.
Looking at Vertex's growth, its revenue over the trailing twelve months (TTM) was $11B. Compared to the same quarter last year (YoY), quarterly revenue grew by 12.10%, and quarterly earnings saw a YoY growth of 12.06%.
Wondering who owns Vertex stock? Company insiders (like executives and directors) hold about 0.14% of the shares, while institutional investors (such as mutual funds and pension funds) own approximately 99.81%.

For more common questions about our data, please visit our About Data page.

Data is provided for informational purposes only. Devyara does not guarantee the accuracy of the data displayed.