Axsome Therapeutics Performance Comparison

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Stock Range

Today's Range

Low: $118.71 High: $124.12
on October 9, 2025

52 Week Range

Low: $75.56 High: $139.13
on December 30, 2024
on February 21, 2025

All-Time High: $139.13 on February 17, 2025

Explore how other US stocks compare to their 52-week ranges: View US Market 52-Week Insights

Key Statistics

Market Cap i $5.9B
EPS i -5.07
P/E Ratio (TTM) i -19.92
Forward P/E i -54.93
P/B Ratio i 80.87
PEG Ratio i 0.48
Div. Yield i N/A
ROE i -280.69%
Beta i 0.513
Debt to Equity i 297.38

Financial Highlights

Profitability

Gross Margin i 91.04%
Operating Margin i -29.87%
Profit Margin i -49.88%

Returns and Earnings

Return on Assets (TTM) i -21.90%
Return on Equity (TTM) i -280.69%
EBITDA i $-199.6M
Net Income (TTM) i $-246.9M

Growth

Revenue (TTM) i
Revenue Per Share (TTM) i $10.17
Quarterly Revenue Growth (YoY) i 72.10%
Quarterly Earnings Growth (YoY) i 72.13%

Peer Performance Comparison

Performance comparison table showing returns for peer companies over various time periods
Company Market Cap 1W 1M 3M 6M YTD 1Y 3Y 5Y
Axsome Therapeutics AXSM 5.92B Mid-cap 2.15% -2.51% 9.05% 20.51% 40.31% 39.93% 155.25% 66.15%
Vertex VRTX 107.98B Large-cap 1.47% 4.64% -13.38% -13.98% 2.24% -13.88% 41.49% 90.23%
Alnylam ALNY 60.24B Large-cap -0.88% -5.22% 42.41% 87.84% 95.60% 60.72% 146.29% 214.27%
Madrigal MDGL 9.87B Mid-cap -4.75% -4.55% 38.79% 36.42% 36.50% 100.00% 562.08% 242.01%
Bio-Techne TECH 9.80B Mid-cap -3.53% 10.52% 13.90% 10.78% -16.20% -18.35% -15.29% -9.82%
Corcept Therapeutics CORT 9.52B Mid-cap 3.37% 23.18% 24.64% 21.09% 76.83% 94.50% 224.61% 390.89%

Ownership & Short Interest

Insider Ownership i 15.86%
Institutional Ownership i 77.38%
Shares Short i 3M
Short Ratio i 5.84
Short % of Shares Outstanding i 8.24%
Average 10-Day Volume i 411K
Average 90-Day Volume i 535K

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Frequently Asked Questions

In the last 52 weeks, Axsome Therapeutics reached a high of $139.13 (on February 21, 2025) and a low of $75.56 (on December 30, 2024).
Curious about Axsome Therapeutics's size and valuation? Its market capitalization stands at 5.92B. When it comes to valuation, the P/E ratio (trailing twelve months) is -19.92, and the forward P/E (looking ahead) is -54.93.
As for dividends, Axsome Therapeutics isn't currently offering a significant yield, or that specific data isn't available right now.

When looking at Axsome Therapeutics, it can be helpful to see how it compares to other players in its field. Here are a few similar companies or key competitors:

CompanyMkt CapSectorIndustry1Y Return3Y Return
Vertex
VRTX
107.98BHealthcareBiotechnology-13.88%41.49%
Alnylam
ALNY
60.24BHealthcareBiotechnology60.72%146.29%
Madrigal
MDGL
9.87BHealthcareBiotechnology100.00%562.08%
Bio-Techne
TECH
9.80BHealthcareBiotechnology-18.35%-15.29%
Corcept Therapeutics
CORT
9.52BHealthcareBiotechnology94.50%224.61%

For a more comprehensive list, please see the Peer Performance Comparison table on this page.

To get a sense of Axsome Therapeutics's financial health, here are a few key indicators: its Return on Equity (ROE) over the last twelve months is -280.69%, the Debt to Equity ratio from the most recent quarter is 297.38, and its Gross Profit Margin stands at 91.04%.
Looking at Axsome Therapeutics's growth, its revenue over the trailing twelve months (TTM) was $495M. Compared to the same quarter last year (YoY), quarterly revenue grew by 72.10%, and quarterly earnings saw a YoY growth of 72.13%.
Wondering who owns Axsome Therapeutics stock? Company insiders (like executives and directors) hold about 15.86% of the shares, while institutional investors (such as mutual funds and pension funds) own approximately 77.38%.

For more common questions about our data, please visit our About Data page.

Data is provided for informational purposes only. Devyara does not guarantee the accuracy of the data displayed.