52-Week High
$331.49
52-Week Low
$127.99
Market Cap
$7.9B
P/E Ratio
39.86
Div Yield
N/A

Krystal Biotech Performance Comparison

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Stock Range

Today's Range

Low: $314.00 High: $326.11
on June 15, 2026

52 Week Range

Low: $127.99 High: $331.49
on June 18, 2025
on June 12, 2026

All-Time High: $331.49 on June 12, 2026

Explore how other US stocks compare to their 52-week ranges: View US Market 52-Week Insights

Key Statistics

Market Cap i $7.9B
EPS i 6.84
P/E Ratio (TTM) i 39.86
Forward P/E i 25.77
P/B Ratio i 6.53
PEG Ratio i 3.31
Div. Yield i N/A
ROE i 18.91%
Beta i 0.538
Debt to Equity i 0.77

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Financial Highlights

Quarter Income Flow i

Annual Income Flow i

Peer Performance Comparison

Company Market Cap 1W 1M 3M 6M YTD 1Y 3Y 5Y 10Y 15Y 20Y
7.89B Mid-cap 7.62% 6.03% 29.82% 33.65% 31.53% 131.98% 161.83% 386.94% 3,060.74% 3,060.74% 3,060.74%
Vertex
Vertex VRTX
109.45B Large-cap 1.69% 3.09% -3.36% -1.15% -0.37% -2.31% 27.89% 136.85% 413.01% 888.51% 1,245.83%
80.98B Large-cap 0.60% -11.93% -18.75% -18.29% -20.78% 15.66% -21.83% 13.80% 72.82% 1,033.17% 4,804.97%
9.51B Mid-cap 7.77% 11.28% 60.15% 73.28% 41.81% 145.12% 200.20% 278.87% 3,924.76% 2,713.34% 2,713.34%
9.60B Mid-cap 4.46% -22.78% -13.27% -4.29% -7.63% 501.76% 1,560.93% -17.42% -36.07% -36.07% -36.07%
9.07B Mid-cap 6.69% 29.72% 15.08% -4.29% -5.83% 6.89% -31.20% -49.99% 96.15% 179.21% 318.28%

Ownership & Short Interest

Insider Ownership i 11.41%
Institutional Ownership i 98.71%
Shares Short i 3M
Short Ratio i 11.08
Short % of Shares Outstanding i 17.51%
Average 10-Day Volume i 248K
Average 90-Day Volume i 273K

Calculate Your Krystal Biotech Investment Returns

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Long-Term Investment Performance Analysis

Krystal Biotech stock price in Sep 2017 was $10.06, A $1,000.00 lump sum investment in Krystal Biotech made 8 years ago would be worth approximately $32,281.31 today, representing a exceptional return of 3,128.13%. This translates to an annualized return (CAGR) of 48.82%.

8 Years 8 Months Investment Scenario (Sep 2017 - Jun 2026)

Initial Investment $1,000.00
Current Value $32,281.31
Annual Return (CAGR) 48.82%
Shares Owned 99.4

Investment Breakdown

Value Comparison

Disclaimer: This calculator is for informational purposes only and does not consider taxes, fees, or other costs associated with investing. Past performance does not guarantee future results.

Frequently Asked Questions

In the last 52 weeks, Krystal Biotech reached a high of $331.49 (on June 12, 2026) and a low of $127.99 (on June 18, 2025).
Curious about Krystal Biotech's size and valuation? Its market capitalization stands at 7.89B. When it comes to valuation, the P/E ratio (trailing twelve months) is 39.86, and the forward P/E (looking ahead) is 25.77.
As for dividends, Krystal Biotech isn't currently offering a significant yield, or that specific data isn't available right now.

When looking at Krystal Biotech, it can be helpful to see how it compares to other players in its field. Here are a few similar companies or key competitors:

CompanyMkt CapSectorIndustry1Y Return3Y Return
Vertex
VRTX
109.45BHealthcareBiotechnology-2.31%27.89%
Regeneron
REGN
80.98BHealthcareBiotechnology15.66%-21.83%
Axsome Therapeutics
AXSM
9.51BHealthcareBiotechnology145.12%200.20%
Praxis Precision
PRAX
9.60BHealthcareBiotechnology501.76%1,560.93%
Bio-Techne
TECH
9.07BHealthcareBiotechnology6.89%-31.20%

For a more comprehensive list, please see the Peer Performance Comparison table on this page.

To get a sense of Krystal Biotech's financial health, here are a few key indicators: its Return on Equity (ROE) over the last twelve months is 18.91%, the Debt to Equity ratio from the most recent quarter is 0.77, and its Gross Profit Margin stands at 93.85%.
Looking at Krystal Biotech's growth, its revenue over the trailing twelve months (TTM) was $389M. Compared to the same quarter last year (YoY), quarterly revenue grew by 17.50%, and quarterly earnings saw a YoY growth of 13.00%.
Wondering who owns Krystal Biotech stock? Company insiders (like executives and directors) hold about 11.41% of the shares, while institutional investors (such as mutual funds and pension funds) own approximately 98.71%.

For more common questions about our data, please visit our About Data page.

Nippun Rana

Nippun Rana

Chasing the market trend!

Hi, I’m Nippun, a tech enthusiast from Haryana, India. I have been coding since 2010 and using my coding skills in the share market since 2020. I have been coding scripts in Pinescript that work on Tradingview app/web. I love learning about new technology and applying it to solve real-world problems. Coding and share-market are my passions, and I enjoy finding and fixing bugs in code. I aim to share my skill set and experience that can positively impact society. Feel free to connect with me, an...

Data is provided for informational purposes only. Devyara does not guarantee the accuracy of the data displayed.