Opko Health (OPK) | Financial Analysis & Statements
Opko Health Inc. Small-cap Healthcare
TL;DR: Financial Overview - Revenue, Profits & Key Metrics
Latest Quarterly: Dec 2025Income Metrics
Revenue
148.4M
Gross Profit
64.0M
43.13%
Operating Income
-38.3M
-25.81%
Net Income
-31.3M
-21.06%
EPS (Diluted)
$-0.04
Balance Sheet Metrics
Total Assets
1.9B
Total Liabilities
664.0M
Shareholders Equity
1.3B
Debt to Equity
0.52
Cash Flow Metrics
Operating Cash Flow
-21.9M
Free Cash Flow
-28.6M
Revenue & Profitability Trend
Quarter Income Flow
Dec 31, 2025
Annual Income Flow
2025
Opko Health Income Statement From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Revenue | 606.9M | 713.1M | 863.5M | 1.0B | 1.8B |
| Cost of Goods Sold | 400.9M | 494.6M | 545.4M | 716.0M | 1.2B |
| Gross Profit | 205.9M | 218.5M | 318.1M | 288.2M | 581.5M |
| Gross Margin % | 33.9% | 30.6% | 36.8% | 28.7% | 32.8% |
| Operating Expenses | |||||
| Research & Development | 124.0M | 105.2M | 89.6M | 73.9M | 76.8M |
| Selling, General & Administrative | 223.0M | 304.2M | 300.6M | 372.7M | 468.9M |
| Other Operating Expenses | - | - | - | - | - |
| Total Operating Expenses | 347.0M | 409.4M | 390.2M | 446.6M | 545.7M |
| Operating Income | -219.0M | -273.6M | -158.1M | -246.1M | -14.5M |
| Operating Margin % | -36.1% | -38.4% | -18.3% | -24.5% | -0.8% |
| Non-Operating Items | |||||
| Interest Income | 14.8M | 8.4M | 4.0M | 2.0M | 28.0K |
| Interest Expense | 108.5M | 47.5M | 13.5M | 12.1M | 18.9M |
| Other Non-Operating Income | 71.3M | 302.2M | -16.7M | -135.3M | 19.3M |
| Pre-tax Income | -241.4M | -10.4M | -184.3M | -391.5M | -14.0M |
| Income Tax | -15.7M | 42.8M | 4.4M | -63.5M | 15.5M |
| Effective Tax Rate % | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Net Income | -225.7M | -53.2M | -188.9M | -328.4M | -30.1M |
| Net Margin % | -37.2% | -7.5% | -21.9% | -32.7% | -1.7% |
| Key Metrics | |||||
| EBITDA | -142.4M | 39.9M | -65.8M | -291.3M | 49.5M |
| EPS (Basic) | $-0.30 | $-0.08 | $-0.25 | $-0.46 | $-0.05 |
| EPS (Diluted) | $-0.30 | $-0.08 | $-0.25 | $-0.46 | $-0.05 |
| Basic Shares Outstanding | 751132891 | 694019535 | 751716915 | 719060942 | 648077716 |
| Diluted Shares Outstanding | 751132891 | 694019535 | 751716915 | 719060942 | 648077716 |
Income Statement Trend
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Opko Health Balance Sheet From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Assets | |||||
| Current Assets | |||||
| Cash & Equivalents | 369.1M | 431.9M | 95.9M | 153.2M | 134.7M |
| Short-term Investments | - | - | - | - | - |
| Accounts Receivable | 90.3M | 118.0M | 123.4M | 127.3M | 259.6M |
| Inventory | 65.8M | 56.8M | 65.7M | 74.1M | 86.5M |
| Other Current Assets | 8.2M | 10.7M | 7.7M | 6.3M | 6.2M |
| Total Current Assets | 581.9M | 662.1M | 309.5M | 394.5M | 823.0M |
| Non-Current Assets | |||||
| Property, Plant & Equipment | 46.9M | 54.0M | 68.1M | 38.7M | 44.2M |
| Goodwill | 1.7B | 1.9B | 2.1B | 2.2B | 2.0B |
| Intangible Assets | 711.3M | 811.6M | 935.3M | 1.0B | 911.9M |
| Long-term Investments | 3.0K | 3.0K | 2.0K | 28.0K | 16.0K |
| Other Non-Current Assets | 19.5M | 18.5M | 9.1M | 8.7M | 9.5M |
| Total Non-Current Assets | 1.4B | 1.5B | 1.7B | 1.8B | 1.6B |
| Total Assets | 1.9B | 2.2B | 2.0B | 2.2B | 2.4B |
| Liabilities | |||||
| Current Liabilities | |||||
| Accounts Payable | 41.1M | 47.1M | 69.7M | 67.0M | 82.0M |
| Short-term Debt | 22.9M | 29.3M | 43.1M | 51.0M | 28.6M |
| Current Portion of Long-term Debt | - | - | - | - | - |
| Other Current Liabilities | - | - | - | - | 28.2M |
| Total Current Liabilities | 146.7M | 193.1M | 200.1M | 213.5M | 330.0M |
| Non-Current Liabilities | |||||
| Long-term Debt | 373.9M | 475.1M | 283.4M | 254.5M | 226.2M |
| Deferred Tax Liabilities | 126.2M | 140.8M | 126.8M | 126.4M | 148.5M |
| Other Non-Current Liabilities | 11.6M | 11.5M | 12.2M | 11.0M | 9.7M |
| Total Non-Current Liabilities | 517.3M | 641.7M | 422.4M | 392.1M | 384.6M |
| Total Liabilities | 664.0M | 834.8M | 622.5M | 605.6M | 714.6M |
| Equity | |||||
| Common Stock | 7.9M | 7.0M | 7.8M | 7.8M | 6.9M |
| Retained Earnings | -2.3B | -2.1B | -2.0B | -1.8B | -1.5B |
| Treasury Stock | 3.2M | 1.8M | 1.8M | 1.8M | 1.8M |
| Other Equity | - | - | - | - | - |
| Total Shareholders Equity | 1.3B | 1.4B | 1.4B | 1.6B | 1.7B |
| Key Metrics | |||||
| Total Debt | 396.8M | 504.4M | 326.6M | 305.5M | 254.8M |
| Working Capital | 435.2M | 469.0M | 109.4M | 181.0M | 493.0M |
Balance Sheet Composition
Opko Health Cash Flow Statement From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Operating Activities | |||||
| Net Income | -225.7M | -53.2M | -188.9M | -328.4M | -30.1M |
| Depreciation & Amortization | 91.6M | 98.2M | 105.3M | 108.7M | 78.7M |
| Stock-Based Compensation | 10.7M | 11.0M | 11.4M | 18.5M | 13.6M |
| Working Capital Changes | 6.7M | -16.5M | 27.1M | 133.4M | 13.2M |
| Operating Cash Flow | -60.2M | 67.1M | -41.9M | -139.6M | 101.4M |
| Investing Activities | |||||
| Capital Expenditures | 287.0K | 242.0K | 2.7M | 2.0M | 66.0M |
| Acquisitions | 190.1M | 210.4M | -5.0M | -1.8M | -6.0M |
| Investment Purchases | - | - | - | - | - |
| Investment Sales | 52.2M | 166.6M | 364.0K | 115.4M | 8.1M |
| Investing Cash Flow | 242.6M | 377.2M | -1.9M | 115.6M | 68.1M |
| Financing Activities | |||||
| Share Repurchases | -47.0M | -90.2M | - | - | - |
| Dividends Paid | - | - | - | - | - |
| Debt Issuance | 33.0M | 939.4M | 671.7M | 1.1B | 1.7B |
| Debt Repayment | -103.8M | -651.4M | -682.7M | -1.0B | -1.7B |
| Financing Cash Flow | -117.8M | 184.4M | -11.0M | 23.7M | -22.7M |
| Free Cash Flow | -190.8M | -208.5M | -44.5M | -119.8M | 6.2M |
| Net Change in Cash | 64.6M | 628.7M | -54.9M | -251.0K | 146.8M |
Cash Flow Trend
Opko Health Key Financial Ratios
Valuation Ratios
P/E Ratio (TTM)
-4.08
Forward P/E
-3.70
Price to Book
0.73
Price to Sales
1.54
PEG Ratio
0.01
Profitability Ratios
Profit Margin
-37.19%
Operating Margin
-28.98%
Return on Equity
-17.14%
Return on Assets
-6.62%
Financial Health
Current Ratio
3.97
Debt to Equity
31.29
Beta
1.49
Per Share Data
EPS (TTM)
$-0.30
Book Value per Share
$1.67
Revenue per Share
$0.81
Peer Financial Comparison
| Company | Market Cap | P/E Ratio | P/B Ratio | ROE | Profit Margin | Debt/Equity |
|---|---|---|---|---|---|---|
| OPK | 936.6M | -4.08 | 0.73 | -17.14% | -37.19% | 31.29 |
| Thermo Fisher | 174.6B | 25.84 | 3.31 | 13.52% | 15.15% | 82.91 |
| Danaher | 126.4B | 34.61 | 2.40 | 7.08% | 14.89% | 37.17 |
| Genedx Holdings | 1.9B | 724.64 | 6.63 | -7.60% | -4.92% | 36.72 |
| CareDx | 1.1B | 13.98 | 3.37 | -6.27% | -5.62% | 8.64 |
| NeoGenomics | 1.0B | -9.42 | 1.22 | -12.43% | -14.85% | 48.95 |
Financial data is updated regularly. All figures are in the company's reporting currency.






