Uniqure N.V (QURE) | Financial Analysis & Statements
Uniqure N.V. Small-cap Healthcare
TL;DR: Financial Overview - Revenue, Profits & Key Metrics
Latest Quarterly: Dec 2025Income Metrics
Revenue
5.6M
Gross Profit
5.1M
92.19%
Operating Income
-51.5M
-924.82%
Net Income
-37.1M
-666.06%
Balance Sheet Metrics
Total Assets
824.9M
Total Liabilities
626.0M
Shareholders Equity
198.9M
Debt to Equity
3.15
Cash Flow Metrics
Operating Cash Flow
-34.2M
Free Cash Flow
-77.7M
Revenue & Profitability Trend
Quarter Income Flow
Dec 31, 2025
Annual Income Flow
2025
Uniqure N.V Income Statement From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Revenue | 16.1M | 27.1M | 15.8M | 106.5M | 524.0M |
| Cost of Goods Sold | 1.7M | 18.3M | 13.6M | 3.3M | 25.0M |
| Gross Profit | 14.4M | 8.8M | 2.2M | 103.1M | 499.0M |
| Gross Margin % | 89.5% | 32.4% | 14.0% | 96.9% | 95.2% |
| Operating Expenses | |||||
| Research & Development | 140.7M | 143.8M | 214.9M | 197.6M | 143.5M |
| Selling, General & Administrative | 65.3M | 50.7M | 74.6M | 55.1M | 56.3M |
| Other Operating Expenses | -5.7M | -5.6M | -4.4M | -6.4M | -11.4M |
| Total Operating Expenses | 200.3M | 188.9M | 285.1M | 246.3M | 188.4M |
| Operating Income | -187.8M | -182.2M | -282.9M | -143.2M | 310.6M |
| Operating Margin % | -1,166.8% | -671.8% | -1,785.5% | -134.4% | 59.3% |
| Non-Operating Items | |||||
| Interest Income | 17.0M | 21.4M | 19.6M | 609.0K | 162.0K |
| Interest Expense | 62.0M | 63.7M | 41.6M | 11.7M | 7.5M |
| Other Non-Operating Income | 39.5M | -12.6M | -1.7M | 26.0M | 29.5M |
| Pre-tax Income | -193.3M | -237.1M | -306.6M | -128.3M | 332.8M |
| Income Tax | 5.6M | 2.4M | 1.9M | -1.5M | 3.2M |
| Effective Tax Rate % | 0.0% | 0.0% | 0.0% | 0.0% | 1.0% |
| Net Income | -199.0M | -239.6M | -308.5M | -126.8M | 329.6M |
| Net Margin % | -1,236.0% | -883.4% | -1,947.1% | -119.1% | 62.9% |
| Key Metrics | |||||
| EBITDA | -148.7M | -150.2M | -251.4M | -134.0M | 318.1M |
| EPS (Basic) | $-3.46 | $-4.92 | $-6.47 | $-2.71 | $7.17 |
| EPS (Diluted) | $-3.46 | $-4.92 | $-6.47 | $-2.71 | $7.04 |
| Basic Shares Outstanding | 57502068 | 48649129 | 47670986 | 46735045 | 45986467 |
| Diluted Shares Outstanding | 57502068 | 48649129 | 47670986 | 46735045 | 45986467 |
Income Statement Trend
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Uniqure N.V Balance Sheet From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Assets | |||||
| Current Assets | |||||
| Cash & Equivalents | 80.2M | 158.9M | 241.4M | 228.0M | 556.3M |
| Short-term Investments | 542.3M | 208.6M | 376.5M | 124.8M | 0 |
| Accounts Receivable | 5.9M | 5.9M | 4.2M | 102.4M | 58.8M |
| Inventory | - | 0 | 12.0M | 6.9M | 0 |
| Other Current Assets | 7.1M | 7.6M | 2.7M | 2.8M | 2.7M |
| Total Current Assets | 656.0M | 390.3M | 651.9M | 476.8M | 628.2M |
| Non-Current Assets | |||||
| Property, Plant & Equipment | 37.5M | 37.0M | 72.4M | 72.1M | 51.1M |
| Goodwill | 123.5M | 115.9M | 113.2M | 109.9M | 118.0M |
| Intangible Assets | 72.8M | 71.0M | 60.5M | 58.8M | 62.7M |
| Long-term Investments | - | - | - | - | - |
| Other Non-Current Assets | 14.2M | 11.3M | 17.6M | 20.6M | 21.5M |
| Total Non-Current Assets | 168.9M | 166.2M | 179.8M | 228.2M | 180.9M |
| Total Assets | 824.9M | 556.5M | 831.7M | 705.0M | 809.2M |
| Liabilities | |||||
| Current Liabilities | |||||
| Accounts Payable | 5.2M | 7.2M | 6.6M | 11.0M | 2.5M |
| Short-term Debt | 3.9M | 3.6M | 8.3M | 8.4M | 5.8M |
| Current Portion of Long-term Debt | - | - | - | - | - |
| Other Current Liabilities | 23.5M | 6.5M | 29.6M | 26.0M | - |
| Total Current Liabilities | 62.9M | 40.1M | 73.7M | 75.9M | 36.8M |
| Non-Current Liabilities | |||||
| Long-term Debt | 59.5M | 62.5M | 130.1M | 134.5M | 130.0M |
| Deferred Tax Liabilities | 8.0M | 7.0M | 7.5M | 8.3M | 12.9M |
| Other Non-Current Liabilities | 495.6M | 453.7M | 412.7M | 10.3M | 33.8M |
| Total Non-Current Liabilities | 563.1M | 523.2M | 550.3M | 153.0M | 176.6M |
| Total Liabilities | 626.0M | 563.3M | 624.0M | 229.0M | 213.4M |
| Equity | |||||
| Common Stock | 3.7M | 2.9M | 2.9M | 2.8M | 2.8M |
| Retained Earnings | -1.3B | -1.1B | -890.4M | -581.9M | -455.1M |
| Treasury Stock | - | - | - | - | - |
| Other Equity | - | - | - | - | - |
| Total Shareholders Equity | 198.9M | -6.8M | 207.7M | 476.0M | 595.8M |
| Key Metrics | |||||
| Total Debt | 63.4M | 66.1M | 138.4M | 142.9M | 135.7M |
| Working Capital | 593.1M | 350.2M | 578.2M | 400.9M | 591.5M |
Balance Sheet Composition
Uniqure N.V Cash Flow Statement From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Operating Activities | |||||
| Net Income | -199.0M | -239.6M | -308.5M | -126.8M | 329.6M |
| Depreciation & Amortization | 14.8M | 12.6M | 11.9M | 8.5M | 7.3M |
| Stock-Based Compensation | 17.7M | 22.3M | 35.1M | 34.2M | 25.6M |
| Working Capital Changes | -11.3M | 1.7M | 87.8M | -46.8M | -59.7M |
| Operating Cash Flow | -136.6M | -181.6M | -126.2M | -126.4M | 310.1M |
| Investing Activities | |||||
| Capital Expenditures | -439.0K | -11.7M | -7.2M | -17.7M | -17.4M |
| Acquisitions | - | 0 | 0 | -1.9M | -49.9M |
| Investment Purchases | -658.4M | -359.8M | -366.4M | -163.1M | 0 |
| Investment Sales | 337.2M | 534.5M | 167.9M | 0 | 0 |
| Investing Cash Flow | -321.6M | 163.0M | -205.7M | -182.7M | -67.4M |
| Financing Activities | |||||
| Share Repurchases | - | - | - | - | - |
| Dividends Paid | - | - | - | - | - |
| Debt Issuance | - | - | 0 | 0 | 64.1M |
| Debt Repayment | 0 | -53.0M | 0 | 0 | -1.6M |
| Financing Cash Flow | 391.9M | -59.5M | 362.7M | 1.4M | 94.9M |
| Free Cash Flow | -178.4M | -194.4M | -153.1M | -162.7M | 270.5M |
| Net Change in Cash | -66.3M | -78.1M | 30.9M | -307.7M | 337.6M |
Cash Flow Trend
Uniqure N.V Key Financial Ratios
Valuation Ratios
P/E Ratio (TTM)
-5.07
Forward P/E
-6.52
Price to Book
5.57
Price to Sales
69.06
PEG Ratio
-6.52
Profitability Ratios
Profit Margin
89.53%
Operating Margin
-900.93%
Return on Equity
-207.10%
Return on Assets
-16.21%
Financial Health
Current Ratio
10.43
Debt to Equity
269.78
Beta
0.75
Per Share Data
EPS (TTM)
$-3.46
Book Value per Share
$3.19
Revenue per Share
$0.28
Peer Financial Comparison
| Company | Market Cap | P/E Ratio | P/B Ratio | ROE | Profit Margin | Debt/Equity |
|---|---|---|---|---|---|---|
| QURE | 1.1B | -5.07 | 5.57 | -207.10% | 89.53% | 269.78 |
| Vertex | 109.4B | 28.40 | 5.92 | 22.54% | 32.94% | 10.91 |
| Regeneron | 81.0B | 18.00 | 2.45 | 14.86% | 31.41% | 9.51 |
| Recursion | 1.9B | -2.44 | 1.64 | -59.54% | 4.45% | 6.89 |
| Capricor | 2.0B | -15.61 | 6.62 | -46.56% | 0.00% | 4.75 |
| Zymeworks | 2.0B | 3.79 | 7.32 | -26.72% | -76.56% | 6.80 |
Financial data is updated regularly. All figures are in the company's reporting currency.






