Silence Therapeutics (SLN) | Financial Analysis & Statements
Silence Therapeutics plc ADR Small-cap Healthcare
TL;DR: Financial Overview - Revenue, Profits & Key Metrics
Latest Quarterly: Dec 2025Income Metrics
Revenue
34.0K
Gross Profit
22.0K
64.71%
Operating Income
-12.5M
-36,650.00%
Net Income
-11.8M
-34,617.65%
Balance Sheet Metrics
Total Assets
131.4M
Total Liabilities
69.1M
Shareholders Equity
62.3M
Debt to Equity
1.11
Cash Flow Metrics
Operating Cash Flow
-13.9M
Free Cash Flow
-17.3M
Revenue & Profitability Trend
Quarter Income Flow
Dec 31, 2025
Annual Income Flow
2025
Silence Therapeutics Income Statement From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Revenue | 559.0K | 43.3M | 25.4M | 17.5M | 12.4M |
| Cost of Goods Sold | 215.0K | 11.8M | 10.3M | 10.9M | 7.5M |
| Gross Profit | 344.0K | 31.4M | 15.1M | 6.6M | 5.0M |
| Gross Margin % | 61.5% | 72.7% | 59.3% | 37.8% | 39.9% |
| Operating Expenses | |||||
| Research & Development | 67.8M | 67.9M | 44.0M | 35.6M | 30.8M |
| Selling, General & Administrative | 22.3M | 26.9M | 20.6M | 19.6M | 20.0M |
| Other Operating Expenses | - | -13.7M | - | - | - |
| Total Operating Expenses | 90.1M | 81.0M | 64.7M | 55.2M | 50.8M |
| Operating Income | -89.8M | -63.3M | -49.6M | -48.6M | -45.8M |
| Operating Margin % | -16,056.0% | -146.4% | -195.5% | -277.7% | -369.0% |
| Non-Operating Items | |||||
| Interest Income | 3.5M | 4.5M | 1.4M | 226.0K | 10.0K |
| Interest Expense | - | - | 34.0K | 47.0K | 8.0K |
| Other Non-Operating Income | -2.3M | 14.4M | -2.1M | 1.0M | -44.0K |
| Pre-tax Income | -88.6M | -44.5M | -50.3M | -47.4M | -45.9M |
| Income Tax | 11.0K | 845.0K | -7.0M | -6.9M | -6.4M |
| Effective Tax Rate % | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Net Income | -88.6M | -45.3M | -43.3M | -40.5M | -39.4M |
| Net Margin % | -15,851.9% | -104.7% | -170.5% | -231.4% | -317.4% |
| Key Metrics | |||||
| EBITDA | -79.4M | -63.4M | -47.7M | -47.9M | -45.4M |
| EPS (Basic) | $-1.89 | $-0.99 | $-1.17 | $-1.26 | $-1.33 |
| EPS (Diluted) | $-1.89 | $-0.99 | $-1.17 | $-1.26 | $-1.33 |
| Basic Shares Outstanding | 47231567 | 46250741 | 28803558 | 25934711 | 23884823 |
| Diluted Shares Outstanding | 47231567 | 46250741 | 28803558 | 25934711 | 23884823 |
Income Statement Trend
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Silence Therapeutics Balance Sheet From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Assets | |||||
| Current Assets | |||||
| Cash & Equivalents | 11.3M | 121.3M | 54.0M | 54.8M | 73.5M |
| Short-term Investments | 73.8M | 26.0M | 0 | 16.3M | 0 |
| Accounts Receivable | 0 | 972.0K | 228.0K | 915.0K | 331.0K |
| Inventory | - | - | - | - | - |
| Other Current Assets | - | - | - | - | - |
| Total Current Assets | 118.7M | 187.4M | 81.0M | 96.7M | 86.3M |
| Non-Current Assets | |||||
| Property, Plant & Equipment | 167.0K | 157.0K | 503.0K | 498.0K | 345.0K |
| Goodwill | 21.5M | 19.1M | 16.0M | 16.3M | 15.2M |
| Intangible Assets | 288.0K | 312.0K | 284.0K | 320.0K | 24.0K |
| Long-term Investments | - | - | - | - | - |
| Other Non-Current Assets | - | - | - | - | - |
| Total Non-Current Assets | 12.8M | 15.3M | 12.8M | 10.8M | 9.9M |
| Total Assets | 131.4M | 202.6M | 93.8M | 107.5M | 96.2M |
| Liabilities | |||||
| Current Liabilities | |||||
| Accounts Payable | 4.4M | 3.7M | 2.6M | 3.2M | 4.1M |
| Short-term Debt | 89.0K | 117.0K | 179.0K | 446.0K | 137.0K |
| Current Portion of Long-term Debt | - | - | - | - | - |
| Other Current Liabilities | - | - | - | - | - |
| Total Current Liabilities | 13.6M | 16.8M | 17.8M | 21.9M | 15.2M |
| Non-Current Liabilities | |||||
| Long-term Debt | 71.0K | 0 | 93.0K | 0 | - |
| Deferred Tax Liabilities | - | - | - | - | - |
| Other Non-Current Liabilities | - | - | - | - | - |
| Total Non-Current Liabilities | 55.5M | 51.8M | 59.0M | 63.5M | 72.5M |
| Total Liabilities | 69.1M | 68.6M | 76.8M | 85.4M | 87.7M |
| Equity | |||||
| Common Stock | 10.3M | 10.3M | 5.9M | 5.4M | 4.5M |
| Retained Earnings | -562.6M | -474.0M | -304.6M | -263.3M | -223.0M |
| Treasury Stock | - | - | - | - | - |
| Other Equity | - | - | - | - | - |
| Total Shareholders Equity | 62.3M | 134.0M | 17.0M | 22.1M | 8.5M |
| Key Metrics | |||||
| Total Debt | 160.0K | 117.0K | 272.0K | 446.0K | 137.0K |
| Working Capital | 105.0M | 170.5M | 63.3M | 74.7M | 71.2M |
Balance Sheet Composition
Silence Therapeutics Cash Flow Statement From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Operating Activities | |||||
| Net Income | -88.6M | -45.3M | -50.3M | -47.4M | -45.9M |
| Depreciation & Amortization | 555.0K | 593.0K | 498.0K | 482.0K | 427.0K |
| Stock-Based Compensation | 8.1M | 16.3M | 13.0M | 10.3M | 8.6M |
| Working Capital Changes | 14.2M | -33.5M | -11.7M | -9.7M | 36.4M |
| Operating Cash Flow | -69.2M | -65.6M | -47.8M | -47.6M | 4.1M |
| Investing Activities | |||||
| Capital Expenditures | -55.0K | -211.0K | -45.0K | -140.0K | -1.3M |
| Acquisitions | - | - | - | - | - |
| Investment Purchases | -166.4M | -139.2M | -20.7M | -16.1M | 0 |
| Investment Sales | 118.5M | 117.4M | 36.2M | 0 | 10.0M |
| Investing Cash Flow | -48.0M | -22.0M | 15.5M | -16.3M | 8.7M |
| Financing Activities | |||||
| Share Repurchases | - | - | - | - | - |
| Dividends Paid | - | - | - | - | - |
| Debt Issuance | - | - | - | - | - |
| Debt Repayment | - | - | -174.0K | -190.0K | -211.0K |
| Financing Cash Flow | 15.0K | 142.1M | 25.2M | 43.0M | 30.7M |
| Free Cash Flow | -62.3M | -67.9M | -39.4M | -45.9M | 5.5M |
| Net Change in Cash | -117.2M | 54.6M | -7.1M | -20.8M | 43.5M |
Cash Flow Trend
Silence Therapeutics Key Financial Ratios
Valuation Ratios
P/E Ratio (TTM)
-4.16
Forward P/E
-11.07
Price to Book
6.04
Price to Sales
673.44
PEG Ratio
-11.07
Profitability Ratios
Profit Margin
61.54%
Operating Margin
-37,150.00%
Return on Equity
-90.27%
Return on Assets
-30.79%
Financial Health
Current Ratio
8.72
Debt to Equity
0.26
Beta
1.33
Per Share Data
EPS (TTM)
$-1.89
Book Value per Share
$1.32
Revenue per Share
$0.01
Peer Financial Comparison
| Company | Market Cap | P/E Ratio | P/B Ratio | ROE | Profit Margin | Debt/Equity |
|---|---|---|---|---|---|---|
| SLN | 370.3M | -4.16 | 6.04 | -90.27% | 61.54% | 0.26 |
| Vertex | 109.4B | 28.40 | 5.92 | 22.54% | 32.94% | 10.91 |
| Regeneron | 81.0B | 18.00 | 2.45 | 14.86% | 31.41% | 9.51 |
| Recursion | 1.9B | -2.44 | 1.64 | -59.54% | 4.45% | 6.89 |
| Capricor | 2.0B | -15.61 | 6.62 | -46.56% | 0.00% | 4.75 |
| Zymeworks | 2.0B | 3.79 | 7.32 | -26.72% | -76.56% | 6.80 |
Financial data is updated regularly. All figures are in the company's reporting currency.






