Taysha Gene (TSHA) | Financial Analysis & Statements
Taysha Gene Therapies Inc. Small-cap Healthcare
TL;DR: Financial Overview - Revenue, Profits & Key Metrics
Latest Quarterly: Dec 2025Income Metrics
Revenue
5.5M
Operating Income
-28.3M
-515.95%
Net Income
-27.9M
-507.77%
Balance Sheet Metrics
Total Assets
343.3M
Total Liabilities
96.4M
Shareholders Equity
246.9M
Debt to Equity
0.39
Cash Flow Metrics
Operating Cash Flow
-28.0M
Free Cash Flow
-27.0M
Revenue & Profitability Trend
Quarter Income Flow
Dec 31, 2025
Annual Income Flow
2025
Taysha Gene Income Statement From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Revenue | 9.8M | 8.3M | 15.5M | 2.5M | 0 |
| Cost of Goods Sold | - | - | - | - | - |
| Gross Profit | - | - | - | - | - |
| Gross Margin % | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Operating Expenses | |||||
| Research & Development | 86.4M | 66.0M | 56.8M | 91.2M | 131.9M |
| Selling, General & Administrative | 33.9M | 29.0M | 30.0M | 37.4M | 41.3M |
| Other Operating Expenses | - | - | - | - | - |
| Total Operating Expenses | 120.3M | 95.0M | 86.8M | 128.5M | 173.3M |
| Operating Income | -110.5M | -86.6M | -71.4M | -126.0M | -173.3M |
| Operating Margin % | -1,130.6% | -1,039.5% | -461.9% | -5,037.1% | 0.0% |
| Non-Operating Items | |||||
| Interest Income | 9.2M | 6.9M | 3.6M | 249.0K | 172.0K |
| Interest Expense | 63.0K | 102.0K | 5.0M | 3.8M | 1.4M |
| Other Non-Operating Income | -7.7M | -9.5M | -38.8M | -36.4M | - |
| Pre-tax Income | -109.0M | -89.3M | -111.6M | -166.0M | -174.5M |
| Income Tax | - | - | - | - | - |
| Effective Tax Rate % | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Net Income | -109.0M | -89.3M | -111.6M | -166.0M | -174.5M |
| Net Margin % | -1,115.3% | -1,071.6% | -722.1% | -6,635.3% | 0.0% |
| Key Metrics | |||||
| EBITDA | -106.6M | -83.1M | -68.0M | -124.6M | -172.6M |
| EPS (Basic) | - | $-0.36 | $-0.96 | $-3.78 | $-4.64 |
| EPS (Diluted) | - | $-0.36 | $-0.96 | $-3.78 | $-4.64 |
| Basic Shares Outstanding | - | 250134421 | 116121482 | 43952015 | 37650566 |
| Diluted Shares Outstanding | - | 250134421 | 116121482 | 43952015 | 37650566 |
Income Statement Trend
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Taysha Gene Balance Sheet From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Assets | |||||
| Current Assets | |||||
| Cash & Equivalents | 319.8M | 139.0M | 143.9M | 87.9M | 149.1M |
| Short-term Investments | - | - | - | - | - |
| Accounts Receivable | - | - | - | - | - |
| Inventory | - | - | - | - | - |
| Other Current Assets | 802.0K | 308.0K | 292.0K | 466.0K | 863.0K |
| Total Current Assets | 324.6M | 142.1M | 149.9M | 96.4M | 159.6M |
| Non-Current Assets | |||||
| Property, Plant & Equipment | 12.7M | 11.5M | 12.4M | 13.8M | 1.1M |
| Goodwill | - | - | - | - | - |
| Intangible Assets | - | - | - | - | - |
| Long-term Investments | - | - | - | - | - |
| Other Non-Current Assets | 2.5M | 2.4M | 2.5M | 4.0M | 4.4M |
| Total Non-Current Assets | 18.7M | 18.2M | 22.9M | 29.9M | 54.4M |
| Total Assets | 343.3M | 160.4M | 172.7M | 126.3M | 214.0M |
| Liabilities | |||||
| Current Liabilities | |||||
| Accounts Payable | 6.3M | 3.6M | 6.4M | 10.9M | 21.8M |
| Short-term Debt | 1.9M | 1.9M | 1.6M | 1.5M | - |
| Current Portion of Long-term Debt | - | - | - | - | - |
| Other Current Liabilities | 777.0K | 1.2M | 1.2M | 650.0K | 1.5M |
| Total Current Liabilities | 26.6M | 26.2M | 36.8M | 62.8M | 51.7M |
| Non-Current Liabilities | |||||
| Long-term Debt | 68.3M | 61.3M | 59.5M | 58.4M | 63.1M |
| Deferred Tax Liabilities | - | - | - | - | - |
| Other Non-Current Liabilities | 1.6M | 1.3M | 1.6M | 4.1M | 3.7M |
| Total Non-Current Liabilities | 69.8M | 62.6M | 61.0M | 62.5M | 66.8M |
| Total Liabilities | 96.4M | 88.8M | 97.8M | 125.3M | 118.6M |
| Equity | |||||
| Common Stock | 3.0K | 2.0K | 2.0K | 1.0K | 0 |
| Retained Earnings | -711.3M | -602.3M | -513.0M | -401.4M | -235.6M |
| Treasury Stock | - | - | - | - | - |
| Other Equity | - | - | - | - | - |
| Total Shareholders Equity | 246.9M | 71.5M | 74.9M | 949.0K | 95.4M |
| Key Metrics | |||||
| Total Debt | 70.1M | 63.2M | 61.1M | 59.9M | 63.1M |
| Working Capital | 298.1M | 115.9M | 113.1M | 33.6M | 107.9M |
Balance Sheet Composition
Taysha Gene Cash Flow Statement From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Operating Activities | |||||
| Net Income | -109.0M | -89.3M | -111.6M | -166.0M | -174.5M |
| Depreciation & Amortization | 1.1M | 1.2M | 1.4M | 1.2M | 492.0K |
| Stock-Based Compensation | 13.3M | 13.1M | 7.9M | 18.0M | 18.2M |
| Working Capital Changes | -9.9M | -11.3M | -17.7M | 25.8M | 14.5M |
| Operating Cash Flow | -98.8M | -84.8M | -110.8M | -117.6M | -131.2M |
| Investing Activities | |||||
| Capital Expenditures | -738.0K | -374.0K | -3.9M | -20.6M | -15.3M |
| Acquisitions | - | - | - | - | - |
| Investment Purchases | - | - | - | - | - |
| Investment Sales | - | - | - | - | - |
| Investing Cash Flow | -604.0K | -363.0K | -3.9M | -20.7M | -15.3M |
| Financing Activities | |||||
| Share Repurchases | - | - | - | - | - |
| Dividends Paid | - | - | - | - | - |
| Debt Issuance | 49.9M | 0 | 39.6M | 0 | 40.0M |
| Debt Repayment | -40.6M | 0 | -43.0M | 0 | 0 |
| Financing Cash Flow | 273.2M | 76.6M | 136.3M | 51.8M | 39.1M |
| Free Cash Flow | -93.8M | -81.6M | -80.4M | -113.3M | -138.6M |
| Net Change in Cash | 173.8M | -8.6M | 21.7M | -86.4M | -107.4M |
Cash Flow Trend
Taysha Gene Key Financial Ratios
Valuation Ratios
P/E Ratio (TTM)
2.53
Forward P/E
-15.71
Price to Book
7.39
Price to Sales
188.17
PEG Ratio
-15.71
Profitability Ratios
Profit Margin
0.00%
Operating Margin
-515.95%
Return on Equity
-68.45%
Return on Assets
-27.42%
Financial Health
Current Ratio
12.23
Debt to Equity
28.41
Beta
1.08
Per Share Data
EPS (TTM)
$-0.34
Book Value per Share
$0.87
Revenue per Share
$0.03
Peer Financial Comparison
| Company | Market Cap | P/E Ratio | P/B Ratio | ROE | Profit Margin | Debt/Equity |
|---|---|---|---|---|---|---|
| TSHA | 1.8B | 2.53 | 7.39 | -68.45% | 0.00% | 28.41 |
| Vertex | 109.4B | 28.40 | 5.92 | 22.54% | 32.94% | 10.91 |
| Regeneron | 81.0B | 18.00 | 2.45 | 14.86% | 31.41% | 9.51 |
| Capricor | 2.0B | -15.61 | 6.62 | -46.56% | 0.00% | 4.75 |
| Zymeworks | 2.0B | 3.79 | 7.32 | -26.72% | -76.56% | 6.80 |
| Amylyx | 1.9B | 2.54 | 6.31 | -61.59% | 0.00% | 1.95 |
Financial data is updated regularly. All figures are in the company's reporting currency.






