Xeris Biopharma (XERS) | Financial Analysis & Statements
Xeris Biopharma Holdings Inc. Small-cap Healthcare
TL;DR: Financial Overview - Revenue, Profits & Key Metrics
Latest Quarterly: Dec 2025Income Metrics
Revenue
85.8M
Gross Profit
74.9M
87.24%
Operating Income
16.8M
19.55%
Net Income
11.1M
12.91%
EPS (Diluted)
$0.06
Balance Sheet Metrics
Total Assets
383.5M
Total Liabilities
369.8M
Shareholders Equity
13.7M
Debt to Equity
27.02
Cash Flow Metrics
Operating Cash Flow
19.1M
Free Cash Flow
19.7M
Revenue & Profitability Trend
Quarter Income Flow
Dec 31, 2025
Annual Income Flow
2025
Xeris Biopharma Income Statement From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Revenue | 291.8M | 203.1M | 163.9M | 110.2M | 49.6M |
| Cost of Goods Sold | 42.6M | 36.8M | 28.6M | 22.6M | 13.3M |
| Gross Profit | 249.3M | 166.2M | 135.3M | 87.6M | 36.3M |
| Gross Margin % | 85.4% | 81.9% | 82.5% | 79.5% | 73.1% |
| Operating Expenses | |||||
| Research & Development | 31.2M | 25.6M | 22.3M | 21.0M | 25.2M |
| Selling, General & Administrative | 182.4M | 163.5M | 146.1M | 137.7M | 125.7M |
| Other Operating Expenses | - | - | - | - | - |
| Total Operating Expenses | 213.5M | 189.0M | 168.4M | 158.7M | 150.9M |
| Operating Income | 24.9M | -33.6M | -44.0M | -81.9M | -115.2M |
| Operating Margin % | 8.5% | -16.6% | -26.8% | -74.3% | -232.2% |
| Non-Operating Items | |||||
| Interest Income | 4.7M | 5.3M | 4.8M | 2.6M | 313.0K |
| Interest Expense | 29.1M | 30.5M | 26.6M | 14.1M | 7.2M |
| Other Non-Operating Income | - | 1.7M | 2.4M | -2.6M | -702.0K |
| Pre-tax Income | 554.0K | -57.1M | -63.5M | -96.1M | -122.7M |
| Income Tax | 0 | -2.3M | -1.2M | -1.4M | 0 |
| Effective Tax Rate % | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Net Income | 554.0K | -54.8M | -62.3M | -94.7M | -122.7M |
| Net Margin % | 0.2% | -27.0% | -38.0% | -85.9% | -247.5% |
| Key Metrics | |||||
| EBITDA | 42.3M | -15.7M | -26.1M | -66.7M | -113.0M |
| EPS (Basic) | $0.00 | $-0.37 | $-0.45 | $-0.70 | $-1.55 |
| EPS (Diluted) | $0.00 | $-0.37 | $-0.45 | $-0.70 | $-1.55 |
| Basic Shares Outstanding | 160425198 | 146772758 | 137674857 | 135628721 | 79027062 |
| Diluted Shares Outstanding | 160425198 | 146772758 | 137674857 | 135628721 | 79027062 |
Income Statement Trend
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Xeris Biopharma Balance Sheet From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Assets | |||||
| Current Assets | |||||
| Cash & Equivalents | 111.0M | 71.6M | 67.4M | 122.0M | 67.3M |
| Short-term Investments | - | 0 | 5.0M | 0 | 35.2M |
| Accounts Receivable | 51.0M | 40.4M | 39.2M | 30.8M | 17.5M |
| Inventory | 68.7M | 48.2M | 38.8M | 24.7M | 18.1M |
| Other Current Assets | 9.5M | 7.5M | 5.8M | 9.3M | 4.6M |
| Total Current Assets | 240.3M | 167.7M | 156.3M | 186.8M | 142.6M |
| Non-Current Assets | |||||
| Property, Plant & Equipment | 5.3M | 4.7M | 4.2M | 3.8M | 3.7M |
| Goodwill | 133.8M | 144.6M | 155.5M | 166.3M | 177.2M |
| Intangible Assets | 88.1M | 98.9M | 109.8M | 120.6M | 131.4M |
| Long-term Investments | - | - | - | - | - |
| Other Non-Current Assets | 5.2M | 5.4M | 4.5M | 4.7M | 829.0K |
| Total Non-Current Assets | 143.2M | 155.4M | 166.3M | 157.7M | 161.8M |
| Total Assets | 383.5M | 323.1M | 322.6M | 344.5M | 304.4M |
| Liabilities | |||||
| Current Liabilities | |||||
| Accounts Payable | 3.1M | 2.3M | 11.6M | 4.6M | 8.9M |
| Short-term Debt | 6.2M | 21.2M | 3.5M | 1.6M | - |
| Current Portion of Long-term Debt | - | - | - | - | - |
| Other Current Liabilities | 4.9M | 1.1M | 20.3M | 2.7M | 2.0M |
| Total Current Liabilities | 109.6M | 100.4M | 95.2M | 73.6M | 79.0M |
| Non-Current Liabilities | |||||
| Long-term Debt | 251.9M | 250.3M | 225.7M | 196.5M | 88.1M |
| Deferred Tax Liabilities | - | 0 | 2.3M | 3.5M | 4.9M |
| Other Non-Current Liabilities | 8.4M | 2.0M | 6.2M | 25.7M | 30.2M |
| Total Non-Current Liabilities | 260.3M | 252.2M | 234.2M | 225.7M | 130.1M |
| Total Liabilities | 369.8M | 352.7M | 329.4M | 299.3M | 209.1M |
| Equity | |||||
| Common Stock | 17.0K | 15.0K | 14.0K | 14.0K | 13.0K |
| Retained Earnings | -671.3M | -671.9M | -617.0M | -554.8M | -460.1M |
| Treasury Stock | - | - | - | - | - |
| Other Equity | - | - | - | - | - |
| Total Shareholders Equity | 13.7M | -29.6M | -6.8M | 45.2M | 95.2M |
| Key Metrics | |||||
| Total Debt | 258.1M | 271.4M | 229.2M | 198.1M | 88.1M |
| Working Capital | 130.7M | 67.2M | 61.1M | 113.2M | 63.6M |
Balance Sheet Composition
Xeris Biopharma Cash Flow Statement From 2021 to 2025
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Operating Activities | |||||
| Net Income | 554.0K | -54.8M | -62.3M | -94.7M | -122.7M |
| Depreciation & Amortization | 12.7M | 12.6M | 13.2M | 12.7M | 1.9M |
| Stock-Based Compensation | 22.4M | 18.4M | 10.7M | 12.2M | 11.4M |
| Working Capital Changes | -28.0M | -14.7M | -9.0M | -21.7M | -8.2M |
| Operating Cash Flow | 11.0M | -42.2M | -51.6M | -89.3M | -116.7M |
| Investing Activities | |||||
| Capital Expenditures | - | - | - | - | - |
| Acquisitions | - | - | 0 | 0 | 38.5M |
| Investment Purchases | 0 | -34.5M | -43.7M | 0 | -43.0M |
| Investment Sales | 0 | 40.2M | 40.0M | 35.0M | 103.6M |
| Investing Cash Flow | 0 | 5.8M | -3.7M | 35.0M | 99.0M |
| Financing Activities | |||||
| Share Repurchases | -10.9M | -3.7M | -1.0M | -468.0K | -534.0K |
| Dividends Paid | - | - | - | - | - |
| Debt Issuance | 0 | 50.0M | 0 | 146.2M | 0 |
| Debt Repayment | 0 | -11.8M | 0 | -43.5M | 0 |
| Financing Cash Flow | -1.7M | 34.4M | -2.2M | 126.6M | 26.4M |
| Free Cash Flow | 27.9M | -37.8M | -49.3M | -103.4M | -96.6M |
| Net Change in Cash | 9.3M | -2.0M | -57.5M | 72.3M | 8.8M |
Cash Flow Trend
Xeris Biopharma Key Financial Ratios
Valuation Ratios
Forward P/E
17.02
Price to Book
73.78
Price to Sales
3.58
PEG Ratio
17.02
Profitability Ratios
Profit Margin
0.19%
Operating Margin
19.55%
Return on Equity
4.05%
Return on Assets
4.40%
Financial Health
Current Ratio
2.19
Debt to Equity
1,885.44
Beta
0.99
Per Share Data
EPS (TTM)
$0.00
Book Value per Share
$0.08
Revenue per Share
$1.82
Peer Financial Comparison
| Company | Market Cap | P/E Ratio | P/B Ratio | ROE | Profit Margin | Debt/Equity |
|---|---|---|---|---|---|---|
| XERS | 1.0B | - | 73.78 | 4.05% | 0.19% | 1,885.44 |
| Vertex | 109.4B | 28.40 | 5.92 | 22.54% | 32.94% | 10.91 |
| Regeneron | 81.0B | 18.00 | 2.45 | 14.86% | 31.41% | 9.51 |
| Capricor | 2.0B | -15.61 | 6.62 | -46.56% | 0.00% | 4.75 |
| Zymeworks | 2.0B | 3.79 | 7.32 | -26.72% | -76.56% | 6.80 |
| Amylyx | 1.9B | 2.54 | 6.31 | -61.59% | 0.00% | 1.95 |
Financial data is updated regularly. All figures are in the company's reporting currency.






